Clinical trial Recruiting at 1 site Observational Ages 18 and up

ChatGPT-4 to detect surgical wound infections after colorectal surgery

Official title: Evaluation of ChatGPT-4 for the Detection of Surgical Site Infections From Electronic Health Records After Colorectal Surgery: A Diagnostic Accuracy Study.

Run by Hospital de Granollers · NCT06626399 · Data updated 2026-11-12

We will test whether ChatGPT-4 can accurately find surgical site infections from electronic health records in people having elective colorectal resection.

More Surgical Site Infection trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment1100 (estimated)
SponsorHospital de Granollers
Academic / other
Locations1 site (Granollers, Barcelona)
StatusRecruiting
StartedJanuary 15, 2025
Main results expectedSeptember 30, 2025
Study endsNovember 30, 2025
Registry record updatedAugust 15, 2025
Trial IDNCT06626399 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults undergoing elective colorectal resection with no infection at the time of surgery and no prior intestinal stoma are ideal candidates.

Probably not a fit

Patients who had emergency surgery, had an infection present at the time of operation, or have a previous intestinal stoma are excluded and unlikely to benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will apply the ChatGPT-4o model to electronic health record data — including clinical notes, microbiology reports, and diagnostic codes — from patients who underwent elective colorectal resection at Hospital General de Granollers. The AI will flag suspected surgical site infections at the three CDC anatomical levels and these flags will be compared with the hospital’s standard manual infection-control surveillance over the 30–90 day postoperative period. The observational analysis will report sensitivity, specificity, and agreement with human surveillance and describe cases of disagreement. The goal is to explore whether automated detection can reduce manual workload and speed identification of postoperative infections.

Why it matters

Potential benefit: If successful, this approach could detect infections sooner and more consistently, enabling earlier treatment and fewer complications.

How similar studies have gone: Prior studies using natural language processing and other AI methods for SSI surveillance have shown promising accuracy in retrospective cohorts, but use of ChatGPT-4 for this specific task is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Elective colorectal resection

Exclusion Criteria:

* Emergency surgery
* Infection present at operation
* Previous intestinal stoma

Where it's running

  • Hospital General de Granollers
    Granollers, Barcelona, Spain
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.