ChatGPT-4 to detect surgical wound infections after colorectal surgery
Evaluation of ChatGPT-4 for the Detection of Surgical Site Infections From Electronic Health Records After Colorectal Surgery: A Diagnostic Accuracy Study.
We will test whether ChatGPT-4 can accurately find surgical site infections from electronic health records in people having elective colorectal resection.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Hospital de Granollers Academic / other |
| Locations | 1 site (Granollers, Barcelona) |
| Trial ID | NCT06626399 on ClinicalTrials.gov |
What this trial studies
Researchers will apply the ChatGPT-4o model to electronic health record data — including clinical notes, microbiology reports, and diagnostic codes — from patients who underwent elective colorectal resection at Hospital General de Granollers. The AI will flag suspected surgical site infections at the three CDC anatomical levels and these flags will be compared with the hospital’s standard manual infection-control surveillance over the 30–90 day postoperative period. The observational analysis will report sensitivity, specificity, and agreement with human surveillance and describe cases of disagreement. The goal is to explore whether automated detection can reduce manual workload and speed identification of postoperative infections.
Who should consider this trial
Good fit: Adults undergoing elective colorectal resection with no infection at the time of surgery and no prior intestinal stoma are ideal candidates.
Not a fit: Patients who had emergency surgery, had an infection present at the time of operation, or have a previous intestinal stoma are excluded and unlikely to benefit.
Why it matters
Potential benefit: If successful, this approach could detect infections sooner and more consistently, enabling earlier treatment and fewer complications.
How similar studies have performed: Prior studies using natural language processing and other AI methods for SSI surveillance have shown promising accuracy in retrospective cohorts, but use of ChatGPT-4 for this specific task is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Elective colorectal resection Exclusion Criteria: * Emergency surgery * Infection present at operation * Previous intestinal stoma
Where this trial is running
Granollers, Barcelona
- Hospital General de Granollers — Granollers, Barcelona, Spain (Recruiting)
Study contacts
- Study coordinator: Josep Badia, MD, PhD
- Email: jmbadiaperez@gmail.com
- Phone: 670702099
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.