Skin staples vs polypropylene skin sutures after elective laparotomy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized trial compares two skin closure methods—skin staples and polypropylene sutures—following elective laparotomy at PIMS in Islamabad. Adults aged 15–50 without major comorbidity are randomized 1:1 to receive either closure method. The primary outcomes are time to skin closure and the rate of surgical site infection within 30 days post-surgery; secondary outcomes include wound dehiscence. The study aims to clarify which technique provides a safer and more efficient closure in a low- to middle-income country setting. Results could inform best practices for postoperative care and potentially reduce infection-related morbidity and costs.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Age 15-50 years Elective laparotomy ASA I-III Written informed consent Male or female

Exclusion Criteria:

Emergency surgery Previous SSI Recurrent surgery BMI \<18 or \>30 kg/m² Haemoglobin \<10 g/dL COPD Stroke Renal failure Liver disease Haematological disorders Malignancy Immunocompromised state Active infection Previous chemotherapy Previous radiotherapy Malnutrition

Where it's running

• Pakistan Institute of Medical Sciences
  Islamabad, Capital, Pakistan Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Silver foam dressing after cesarean: does it prevent infection as well as standard care?

  This trial tests whether a silver-containing foam dressing worn over cesarean incisions is no worse than standard dressings at preventing surgical site infections.

  Recruiting Montefiore Medical Center · The Bronx, New York · NCT07914569

• Hernia Sac Flap Coverage of Mesh in Complex Bony-Edged Ventral Hernias

  We’re testing whether using the patient’s own hernia sac as a living flap underneath the mesh helps healing after complex ventral hernia repair when part of the edge is bone.

  Recruiting Minia University · Minya, Minya Governorate · NCT07720154

• Steri-Strips added to standard wound closure after cesarean delivery

  This study tests whether adding Steri-Strips after a C-section helps reduce wound problems for pregnant patients.

  Recruiting Riverside University Health System Medical Center · Moreno Valley, California · NCT07686913

• Cold atmospheric plasma to improve cannulation-site wound healing after extracorporeal life support

  This trial will test whether adding cold atmospheric plasma (CAP) to standard wound care helps adults on extracorporeal life support heal cannulation-site wounds faster and with fewer infections.

  Recruiting National Taiwan University Hospital · Taipei · NCT07501897

• Preventing wound infections in children having open groin surgery with IV antibiotics or antimicrobial-coated sutures

  This will test whether a single IV antibiotic dose or antimicrobial-coated sutures prevent wound infections in children having open groin surgery.

  Recruiting Obafemi Awolowo University Teaching Hospital · Ile-Ife, Osun State · NCT07346742

• Local subcutaneous gentamicin to prevent surgical site infections after elective cesarean section

  This trial tests whether injecting a small dose of gentamicin under the skin at the incision lowers the chance of surgical site infection after an elective cesarean delivery.

  Recruiting Western Galilee Hospital-Nahariya · Nahariya · NCT07311395

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.