Preventing wound infections in children having open groin surgery with IV antibiotics or antimicrobial-coated sutures

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a double-blinded, randomized three-arm trial enrolling children scheduled for daycase open groin surgery (inguinal hernia or hydrocele) at a single tertiary hospital. On the morning of surgery participants are randomly assigned to receive IV cefuroxime or placebo and to have wounds closed with either antimicrobial-coated or standard sutures, creating comparison groups for no antibiotic, IV antibiotic, and coated-suture strategies. Surgical site infection will be recorded at postoperative visits on days 5, 13, and 30 using predefined clinical criteria. The trial compares infection rates between the groups to see which intervention, if any, reduces postoperative wound infections.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* All patients with clinical conditions requiring daycase open groin surgery

Exclusion Criteria:

1. Re-operations
2. Immunocompromised patients
3. Malnourished patients
4. Complicated groin pathologies e,g obstructed inguinal hernia
5. History of antibiotic usage in the last seven days

Where it's running

• Obafemi Awolowo University Teaching Hospitals Complex
  Ile-Ife, Osun State, Nigeria Recruiting

Study contacts

• Study coordinator: Olawumi Olajide, M.B.Ch.B
• Email: yejola1212@gmail.com
• Phone: +2348038696179

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.