Cention-N, Zirconomer, and Resin-modified Glass Ionomer for Class I fillings in kids' primary molars
Official title: Evaluation of the Clinical Performance, Streptococcus Mutans Count, and Salivary pH for Cention-N, Zirconomer, and Resin-modified Glass Ionomer in Class I Restoration of Primary Molars: A Randomized Clinical Trial
Run by Al-Azhar University · NCT07776912 · Data updated 2026-11-12
This study tests three materials (Cention-N, Zirconomer, and resin-modified glass ionomer) to see how they perform in filling primary molars of children aged 4 to 9 and how they affect Streptococcus mutans counts and saliva pH.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 4 Years to 9 Years |
| Sex | All |
| Enrollment | 45 (estimated) |
| Sponsor | Al-Azhar University Academic / other |
| Locations | 1 site (Cairo) |
| Status | Recruiting |
| Started | August 1, 2025 |
| Main results expected | December 1, 2027 |
| Study ends | December 1, 2027 |
| Registry record updated | August 20, 2026 |
| Trial ID | NCT07776912 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Children aged 4-9 with Class I lesions in primary molars in both arches, tooth structure suitable for restoration, and no periapical pathology or root resorption.
✕Probably not a fit
Children with complex cases, nonfunctional teeth, or teeth requiring extraction may not benefit from these materials.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The trial compares three restorative materials used for Class I lesions in primary molars of children aged 4-9. It will measure clinical performance, Streptococcus mutans counts, and salivary pH to evaluate how each material behaves over time. The study design is interventional and involves real-life clinical restorations performed in pediatric patients. Eligible participants have lesions in both arches with suitable tooth structure and no periapical pathology or significant mobility. Results may inform choice of restorative material based on bacterial activity, acidity, and durability in the primary dentition.
Why it matters
Potential benefit: If successful, children may receive restorations with favorable bacterial responses and stable salivary pH, potentially contributing to better oral health outcomes.
How similar studies have gone: Previous work on glass ionomer and resin-modified cements supports their use in pediatric restorations, but direct comparisons in this exact setup are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Children aged between 4-9 years. * Children who have Class I lesions in both the maxillary and mandibular arches. * Primary molar teeth had class I carious lesions in occlusal pits and fissures; the gap between intercuspal surfaces should not be exceeded during cavity preparation. * Primary molars free of periapical pathosis. * Primary molars free root resorption. Exclusion Criteria: * Primary molars with preapical pathosis or hypersensitivity. * Primary molars with periodontal diseases or mobile molar tooth that indicated for extraction. * Nonfunctioning teeth with no opposing dentition; heavy occlusion or signs of severe attrition; and endodontically treated teeth.
Where it's running
-
Al-Azhar University (Faculty of Dentistry)
Cairo, Egypt Recruiting
Study contacts
- Study coordinator: Galal A Elkady, B.Sc
- Email: dr_galal86@yahoo.com
- Phone: 00201001375178
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.