Treating infected non-vital baby molars with a zinc oxide/6-gingerol mix versus a triple antibiotic paste

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares Lesion Sterilization and Tissue Repair (LSTR) using a zinc oxide/6-gingerol mixture versus a conventional triple antibiotic paste in non-vital primary molars. Children aged 4–8 with at least two restorable non-vital primary molars and periapical radiolucency will receive minimal canal instrumentation followed by placement of one of the two medicaments. Clinical signs (pain on mastication, mobility, resolution of symptoms) and radiographic changes (periapical radiolucency, root resorption) will be recorded at scheduled follow-ups to compare healing. The trial is conducted at Al-Azhar University in Cairo to determine whether the zinc oxide/6-gingerol mix can match or improve outcomes compared with the antibiotic paste.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age from 4 to 8 years.
* Both sexes
* Children must have at least two restorable non-vital primary molars
* Periapical radiolucency.
* Pain on mastication.
* Pathological mobility.
* Internal or external root resorption.
* Furcation involvement should not extend to the developing tooth germ.

Exclusion Criteria:

* Presence of systemic diseases.
* Teeth with physiological mobility near exfoliation time.
* Teeth with vital pulp.

Where it's running

• Al-Azhar University
  Cairo, Egypt Recruiting

Study contacts

• Study coordinator: Ahmed E El-Metwally, MBBCH
• Email: ahmedalsaayed647@gmail.com
• Phone: 00201090888701

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.