Comparing probiotic and ethyl lauroyl arginate mouthwashes for lowering cavity‑causing bacteria and plaque in Egyptian schoolchildren

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Children receive professional dental cleaning and are then assigned to use either a probiotic mouthwash or an ethyl lauroyl arginate (LAE) mouthwash over a defined follow-up period. Investigators measure Streptococcus mutans counts, dental plaque accumulation, and salivary pH at baseline and after treatment to compare effects. The trial is conducted at the Faculty of Dentistry, Al‑Azhar University, with eligibility limited to healthy schoolchildren who have mild to moderate plaque and parental consent. Participants with recent antibiotic use, allergies to mouthwash components, systemic disease, orthodontic appliances, or extensive restorations are excluded.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Healthy Egyptian schoolchildren aged 6-12 years.
* Good general health.
* Mild to moderate dental plaque accumulation.
* Parental/caregiver willingness to provide consent

Exclusion Criteria:

* Antibiotic or antimicrobial use within the last month.
* Allergies to the mouthwash components.
* Systemic diseases affecting oral health.
* Orthodontic appliances or extensive dental restorations.

Where it's running

• Al-Azhar University (Faculty of Dentistry)
  Cairo, Egypt Recruiting

Study contacts

• Study coordinator: Mohamed O Abdelrazik, MBBCH
• Email: mohamedghitany96@gmail.com
• Phone: 00201017005990

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.