Can neck vein ultrasound predict low blood pressure and kidney injury during abdominal surgery?

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective, single-center study enrolls adults undergoing major abdominal or visceral surgery under general anesthesia with propofol. It uses bedside ultrasound to measure the internal jugular vein collapsibility index before anesthesia and again after loss of consciousness, comparing changes to intraoperative blood pressure and postoperative kidney function via routine labs. The goal is to see if neck vein measurements can identify patients at risk for induction hypotension and postoperative acute kidney injury. No changes to standard anesthesia care are made; ultrasound and blood tests are added for research purposes. Data will be analyzed to determine whether vein collapsibility indices predict perioperative hemodynamic instability and renal outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Elective or Urgent (Non-emergent) major abdominal/ visceral surgery under general anesthesia
* General anesthesia with propofol induction (TCI/ manual)
* Expected surgical duration \> 60 minutes
* Continous BP monitoring (Invasive arterial line or non-invasive cuff at 2 minute recording intervals)
* Serum creatinine and eGFR (CKD-EPI) available within 30 days prior to surgery
* Written informed consent obtained before surgery
* Patient accessible by phone 30 days postoperatively

Exclusion Criteria:

* Emergency surgery (immediate life-saving, consent unobtainable)
* End-stage renal disease (eGFR \< 15 mL/min/1.73 m²) or dialysis-dependent
* Concomitant cardiac surgery or carotid endarterectomy
* Liver transplantation
* Known Internal Jugular Vein/ Inferior Vena Cava thrombosis or Superior Vena Cava syndrome
* Any anatomical neck abnormalities precluding Internal jugular vein ultrasound
* Induction with ketamine or etomidate as sole Induction agent
* Neuraxial anesthesia (spinal or epidural) before propofol induction
* Active decompensated heart failure (NYHA IV or acute pulmonary edema at time of Surgery)
* Same-admission reoperation within 30-day study window
* Withdrawal of consent at any point

Where it's running

• County Emergency Clinical Hospital of Targu Mureș
  Târgu Mureş, Mureș County, Romania Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.