Brief treatment for anxiety and PTSD in South Africa
Brief Transdiagnostic Treatment for Anxiety Disorders and PTSD in South Africa: A Hybrid-Effectiveness-Implementation Trial
This study is testing a new, simple treatment for anxiety and PTSD in South Africa to see if it helps people feel better compared to regular care.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Massachusetts General Hospital Academic / other |
| Locations | 1 site (Cape Town) |
| Trial ID | NCT06289621 on ClinicalTrials.gov |
What this trial studies
This study evaluates a brief transdiagnostic treatment for anxiety disorders and post-traumatic stress disorder (PTSD) in South Africa, delivered by non-specialist providers in primary care clinics. The intervention, known as False Safety Behavior Elimination Treatment (F-SET), aims to address the high prevalence of these conditions in low and middle-income countries where access to evidence-based treatments is limited. Participants receiving the brief intervention will be compared to those receiving enhanced standard care, allowing for an assessment of both effectiveness and implementation barriers. The study seeks to provide a culturally congruent and less complex treatment option for individuals in need.
Who should consider this trial
Good fit: Ideal candidates include individuals diagnosed with a primary anxiety disorder or PTSD who are seeking treatment in primary care settings.
Not a fit: Patients who are acutely suicidal, have severe substance use disorders, or are currently engaged in other forms of psychotherapy may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve access to effective mental health treatment for anxiety and PTSD in underserved populations.
How similar studies have performed: Other studies have shown promise in using brief, transdiagnostic approaches for mental health treatment, indicating potential for success in this novel application.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Participants diagnosed with a primary anxiety disorder (panic disorder, generalized anxiety disorder, social anxiety disorder, or obsessive-compulsive disorder) or post-traumatic stress disorder. Exclusion Criteria: * Participants who are acutely suicidal, have severe alcohol of substance use disorder, or are engaged in another form of psychotherapy.
Where this trial is running
Cape Town
- Stellenbosch University — Cape Town, South Africa (Recruiting)
Study contacts
- Study coordinator: Kristina Korte, PhD
- Email: kkorte@mgh.harvard.edu
- Phone: 6177268205
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.