Home use of ketamine for chronic conditions

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the safety and efficacy of oral and nasal ketamine administered at home for individuals with chronic conditions, including chronic pain, major depressive disorder, and PTSD. The study aims to recruit up to 50,000 participants over five years, utilizing digital technology to gather data on treatment protocols and outcomes. Participants will be assessed using psychological scales to evaluate the impact of ketamine on their symptoms, with interim results expected in November 2023 and final results in June 2024.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Must have an identifiable chronic condition.

Exclusion Criteria:

Healthy Population

Where it's running

• RIVER Foundation
  Bigfork, Montana, United States Recruiting
• RIVER Telehealth
  Helena, Montana, United States Recruiting

Study contacts

• Principal investigator: Dharma Rose, D.O. M.S. — RIVER Foundation
• Study coordinator: Ed Lesofski, M.S.
• Email: ed@riverofchange.org
• Phone: 406-431-4890

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Evaluating Ketamine Treatment Plans for Chronic Conditions

  This study is testing different ways to use Ketamine for people with chronic pain, depression, and anxiety to see how well it works and if combining it with therapies like talk therapy or music helps improve their conditions.

  Recruiting RIVER Foundation · Helena, Montana · NCT06038409

• Mindful Self-Compassion delivered in person versus by video for anxiety and depression

  This project will see if an 8-week Mindful Self-Compassion class delivered in person or by video helps people with anxiety or depression have fewer symptoms.

  Recruiting Georgetown University · Washington D.C., District of Columbia · NCT07028216

• Identifying genetic markers for SSRI-induced behavioral activation in youth

  This study is trying to find genetic markers that can help predict which children and teens with depression or anxiety might experience increased energy or restlessness from taking certain antidepressants.

  Recruiting at 2 sites University of Manitoba · Winnipeg, Manitoba and 1 other locations · NCT06763081

• Internet-based treatment for anxiety and depression in adolescents

  This study is testing an online treatment for anxiety and depression in Romanian teenagers aged 13-17 to see if it helps them feel better and to find out which teens are most likely to benefit from it.

  Recruiting Babes-Bolyai University · Cluj-Napoca and 1 other locations · NCT06724666

• Improving sleep for Veterans with traumatic brain injury, PTSD, and chronic pain

  We will try morning bright light therapy at home to improve sleep for Veterans who have TBI, PTSD, and chronic pain.

  Recruiting VA Office of Research and Development · Portland, Oregon · NCT06477796

• Brief treatment for anxiety and PTSD in South Africa

  This study is testing a new, simple treatment for anxiety and PTSD in South Africa to see if it helps people feel better compared to regular care.

  Recruiting Massachusetts General Hospital · Cape Town · NCT06289621

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.