Clinical trial Recruiting at 1 site Interventional Ages 18 to 25

Breathing Techniques to Support Stress and Resilience in Physical Therapy Students

Official title: Enhancing Physiological and Psychological Resilience: A Comparative Study of Diaphragmatic and Box Breathing in Physical Therapy Students.

Run by Cairo University · NCT07698652 · Data updated 2026-11-12

This study tests whether diaphragmatic breathing and box breathing can help stressed physical therapy students improve heart rate variability and feel less stressed.

Quick facts

Study typeInterventional
Ages18 Years to 25 Years
SexAll
Enrollment60 (estimated)
SponsorCairo University
Academic / other
Locations1 site (Minya, Minya Province)
StatusRecruiting
StartedSeptember 20, 2026
Main results expectedDecember 30, 2026
Study endsMarch 1, 2027
Registry record updatedSeptember 28, 2026
Trial IDNCT07698652 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are full-time, undergraduate physical therapy students ages 18-25 with moderate to high baseline stress and no major medical or respiratory conditions.

Probably not a fit

Participants with low stress or those with conditions contraindicating breathing exercises may see minimal benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Sixty undergraduate physical therapy students with moderate to high stress will be randomly assigned to diaphragmatic breathing, box breathing, or a no-intervention control group for four weeks. Primary outcome is heart rate variability as a sign of physiological adaptation; secondary outcomes include perceived stress, cognitive performance, and academic achievement. The study uses a structured breathing program with supervised sessions to evaluate safety and feasibility in a healthy student population. Results will inform whether these simple, non-drug techniques can support stress management and resilience in healthcare education.

Why it matters

Potential benefit: If successful, students may experience better stress management and cognitive performance, potentially improving academic outcomes.

How similar studies have gone: Breathing-based interventions have shown promise in reducing stress and improving HRV in other populations, but results vary and this study adds population-specific evidence.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Academic Status: Currently enrolled, full-time undergraduate Physical Therapy students
* Age Range: 18-25 years
* Health Status: Generally healthy individuals with no known chronic respiratory or cardiovascular diseases.
* Informed Consent: Ability and willingness to provide written informed consent and commit to the 4-week protocol (6 sessions/week).
* Stress Level: A baseline score on the Perceived Stress Scale (PSS) indicating at least moderate stress.

Exclusion Criteria:

* Pre-existing Breathing Expertise: Individuals with professional training in yoga (Pranayama), formal meditation, or advanced breath work that might bias the baseline results.
* Medical Conditions: Diagnosed respiratory conditions (e.g., Asthma, COPD).
* Cardiovascular issues (e.g., Arrhythmias, Hypertension).
* Clinical psychological disorders (e.g., Generalized Anxiety Disorder or Panic Disorder) that may require medication.
* Pharmacological Factors: Use of medications that influence the Autonomic Nervous System (e.g., Beta-blockers, antidepressants, or heavy use of stimulants/sedatives).
* Substance Use: Smokers/Vapers
* Excessive Caffeine "Participants consuming more than 400 mg of caffeine per day (equivalent to approximately 4 standard cups of brewed coffee) will be excluded.
* Recent Acute Illness: Any respiratory tract infection or fever within two weeks prior to the start of the study

Where it's running

  • Faculty of Physical Therapy, Deraya University
    Minya, Minya Province, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.