Breakthrough Pain After Brachial Plexus Block in People With Type 2 Diabetes
Official title: An Observational Study on Incidence and Clinical Characteristics of Breakthrough Pain Following Brachial Plexus Block in Adult Patients With Diabetes Mellitus
Run by Second Hospital of Shanxi Medical University · NCT07833930 · Data updated 2026-11-12
This study tests how often rebound pain happens after a nerve block in adults with type 2 diabetes compared with those without diabetes.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 216 (estimated) |
| Sponsor | Second Hospital of Shanxi Medical University Academic / other |
| Locations | 1 site (Taiyuan) |
| Status | Recruiting |
| Started | September 20, 2025 |
| Main results expected | September 20, 2026 |
| Study ends | September 20, 2026 |
| Registry record updated | September 22, 2026 |
| Trial ID | NCT07833930 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18+) undergoing elective upper-extremity surgery planned for ultrasound-guided brachial plexus block with 0.375% ropivacaine.
✕Probably not a fit
Patients without diabetes or those not experiencing rebound pain may see limited direct benefits; results may not apply to other anesthetic techniques.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study follows adults undergoing elective upper-extremity surgery with ultrasound-guided brachial plexus block using ropivacaine to compare postoperative rebound pain between people with type 2 diabetes and non-diabetic controls. Baseline data such as HbA1c and sensory thresholds are collected, and post-block pain scores, block duration, analgesic use, and recovery are recorded for up to 48 hours. The aim is to quantify incidence and characterize the clinical features of rebound-breakthrough pain and its relationship with diabetes status. No experimental interventions are introduced beyond standard anesthesia care. Findings may inform perioperative pain management strategies for diabetic patients receiving nerve blocks.
Why it matters
Potential benefit: If successful, the study could help tailor pain management for diabetic patients to reduce rebound pain and opioid use after brachial plexus block.
How similar studies have gone: Previous work has explored rebound pain after nerve blocks, but data specific to type 2 diabetes and brachial plexus block remains limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged 18 years or older * Undergoing elective upper-extremity surgery * Planned for ultrasound-guided brachial plexus block with 0.375% ropivacaine * Able to cooperate with pain assessment and follow-up within 48 hours after block * Written informed consent obtained Exclusion Criteria: * Allergy or contraindication to amide-type local anesthetics * Pre-existing peripheral neuropathy of the affected upper limb * Chronic regular use of opioids before surgery * Coagulopathy or infection at the block puncture site * Cognitive dysfunction unable to complete NRS pain evaluation * Pregnancy or lactation * Incomplete clinical data expected during follow-up
Where it's running
-
Second Hospital of Shanxi Medical University
Taiyuan, China Recruiting
Study contacts
- Study coordinator: Wen bo Wang
- Email: 1525565253@qq.com
- Phone: +8618636532676
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.