Bioperio® protocol for treating periodontitis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This was a prospective, single-arm, multicenter observational evaluation of a standardized, patient-centered periodontal care pathway called the Bioperio® protocol. The protocol combined supra-gingival scaling, oral hygiene instruction and motivation, full-mouth subgingival instrumentation, and in Stage III/IV cases adjunctive enamel matrix derivative application for deep pockets. Patients were adults with confirmed periodontitis who had not previously received periodontal treatment and who agreed to follow a defined follow-up schedule. Clinical periodontal outcomes such as pocket depth, attachment level changes, and need for further surgical treatment were used to gauge performance of the protocol.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Confirmed diagnosis of periodontitis (proximal attachment loss in ≥2 non-adjacent teeth)
* No previous treatment for periodontitis
* Systemically healthy or with well-controlled chronic medical conditions
* Willingness to participate in the study and comply with the follow-up schedule

Exclusion Criteria:

* Pregnancy or breastfeeding
* Patients previously treated for periodontitis
* Poorly controlled systemic conditions
* Refusal to participate
* Patients who did not complete the proposed treatment plan

Where it's running

• University of Pisa
  Pisa, None Selected, Italy Recruiting

Study contacts

• Study coordinator: Filippo Graziani, Prof.
• Email: filippo.graziani@unipi.it
• Phone: +393384014984

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Boron, Oxidative Stress, and Inflammation in Periodontitis

  This observational study compares boron levels and inflammation markers in saliva and gum tissue between people with periodontitis and healthy controls to see if boron relates to gum inflammation.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.