Biobank for Down Syndrome Research

Research to Develop the Human Trisome Project Biobank

Observational University of Colorado, Denver · NCT02864108

This study is creating a biobank to collect health information and samples from people with Down syndrome to help researchers learn more about the condition and related health issues.

Quick facts

Study typeObservational
Enrollment2500 (estimated)
Ages6 Months to 89 Years
SexAll
SponsorUniversity of Colorado, Denver Academic / other
Locations1 site (Denver, Colorado)
Trial IDNCT02864108 on ClinicalTrials.gov

What this trial studies

The Human Trisome Project aims to enhance Down syndrome research by creating a biobank that provides de-identified biological samples and health information to approved researchers. Participants will undergo a blood draw, mouth swab, and allow researchers to access their health information annually for up to five years. Optional procedures include providing urine and/or stool samples and extending participation beyond five years. This initiative seeks to improve understanding of Down syndrome and related medical conditions such as Alzheimer's disease and congenital heart defects.

Who should consider this trial

Good fit: Ideal candidates include individuals aged 6 months to 89 years who either have Down syndrome or do not have Down syndrome.

Not a fit: Patients who are prisoners or wards of the state will not benefit from this study.

Why it matters

Potential benefit: If successful, this project could accelerate research and lead to better treatments and understanding of Down syndrome and its associated conditions.

How similar studies have performed: Other studies utilizing biobanks for genetic and health research have shown success, indicating that this approach is promising.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Anyone 6 months to 89 years old who:

1. has Down syndrome (any type)
2. does not have Down syndrome

Exclusion Criteria:

1. Prisoners
2. Wards of the state

Where this trial is running

Denver, Colorado

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Down SyndromeTrisomy 21
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.