Kinematic analysis of hand and arm movement in kids with Down syndrome, CP and healthy children

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will use inertial measurement units and the Box and Block Test to collect upper-limb kinematic data in children and adolescents. The goal is to establish normative motion patterns in healthy subjects aged 4–18 and compare them with those of pediatric patients with cerebral palsy-related hemisyndrome and Down syndrome. The study describes inclusion criteria focused on cognitive ability, motor function, and range of motion, while excluding participants with conditions that would confound movement measurements. Data will be analyzed to characterize typical gestures and identify deviations linked to the conditions studied. This is an observational, instrument-based assessment rather than an intervention.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Cognitive state that allows understanding and subsequent correct execution of the motor activity required during the execution of the BBT
* Trunk Control Test: item 3 = 25 (Collin \& Wade, 1990)
* Absence of orthopedic problems at the level of the upper limb

For pyramidal hemisyndrome:

* Moderate/mild motor impairment assessed with:
* Manual Ability Classification System (MACS): with values from 1 to 2 (Eliasson AC et al., 2006)
* Bimanual Fine Motor Function Scale (BFMF): with values from 1 to 4 (Beckung \& Hagberg, 2002)
* Modified Ashworth Scale upper limb (MAS): with values ≤2

For Down syndrome:

-genetic diagnosis

Exclusion Criteria:

* Presence of joint pathologies that limit the range of motion of the upper limbs
* Presence of concomitant neurological pathologies that influence motor function
* Inability (motor, cognitive) to maintain the described position for the time necessary to perform the test
* Lack of collaboration of the subject
* Participants who have not signed the informed consent to the study.

Where it's running

• IRCCS San Raffaele Roma
  Rome, Italiy, Italy Recruiting

Study contacts

• Principal investigator: Dr. Sanaz Pournajaf, DPT, PhD — IRCCS San Raffaele Roma
• Study coordinator: Lucia Gatta, PhD
• Email: lucia.gatta@sanraffaele.it
• Phone: +390652253440

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.