Bowel Sounds and Day-to-Day Recovery After Colorectal Cancer Surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study enrolls adults undergoing curative colorectal cancer surgery. Bowel sounds are recorded preoperatively and postoperatively, and their relationship with recovery metrics such as time to first flatus, first oral intake, and incidence of ileus or other complications is analyzed. The goal is to see if perioperative bowel sound patterns help predict postoperative recovery and guide clinical management within ERAS pathways. Data will be collected on intraoperative variables, perioperative complications, and reoperation rates to understand how bowel motility relates to outcomes. The study is conducted at Zhongnan Hospital of Wuhan University with collaboration from Wuhan University.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Aged 18-80 years.
* Histopathologically confirmed colorectal adenocarcinoma according to the WHO 2022 classification.
* No restriction on prior neoadjuvant or other antitumor therapies, including chemotherapy, radiotherapy, targeted therapy, or immunotherapy.
* Able to understand the study requirements and voluntarily provide written informed consent (patient and/or legally authorized representative).
* Able to communicate effectively with the investigators and willing to comply with all study procedures, including postoperative management and follow-up.

Exclusion Criteria:

* Significant organ dysfunction indicating inability to tolerate surgery or an unacceptably high perioperative risk, including:
* Severe cardiac dysfunction (NYHA Class III or IV).
* Severe hepatic dysfunction (MELD score \>12).
* Severe renal dysfunction (eGFR \<30 mL/min/1.73 m² \[CKD stage 4-5\] or end-stage renal disease requiring dialysis).
* Severe pulmonary dysfunction (resting PaO₂ \<60 mmHg on room air or respiratory failure requiring long-term oxygen therapy or mechanical ventilation).
* Participation in another clinical study within 4 weeks before enrollment or concurrent participation in another interventional clinical study.
* Emergency surgery required because of intestinal obstruction, perforation, or other acute abdominal conditions.
* Severe psychiatric disorders that would interfere with compliance with perioperative management or follow-up.
* Pregnant or breastfeeding women.
* Any other clinical or laboratory abnormality that, in the opinion of the investigator, would make the participant unsuitable for the study.

Where it's running

• Zhongnan Hospital of Wuhan University
  Wuhan, Hubei, China Recruiting

Study contacts

• Study coordinator: siyuan yin, master
• Email: 2023283030136@whu.edu.cn
• Phone: +86 18771708286

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Peripheral autonomic plus TAP blocks for pain after minimally invasive left-sided colorectal surgery

  This will try adding a peripheral autonomic block (targeting the superior hypogastric and inferior mesenteric plexuses) plus a TAP block to standard pain control in adults having elective minimally invasive left-sided colorectal surgery to see if it reduces pain and opioid use in the first 48 hours.

  Recruiting Faculdade de Ciências Médicas de Minas Gerais · Belo Horizonte, Minas Gerais · NCT07388953

• Pre-emptive endoscopic vacuum therapy to reduce anastomotic leaks after colorectal cancer surgery

  This will try using pre-emptive endoscopic vacuum therapy after colorectal cancer surgery to see if it lowers early anastomotic leaks in adults having radical colorectal operations.

  Recruiting Nanchong Central Hospital · Nanchong, Sichuan · NCT07208786

• Thread-embedding acupuncture to speed bowel recovery after colorectal cancer surgery.

  This trial will test whether adding thread embedding acupuncture (with electroacupuncture) helps adults recover bowel function faster after elective laparoscopic colorectal cancer surgery.

  Recruiting Northern Jiangsu People's Hospital · Yangzhou, Jiangsu · NCT07071987

• Testing for leaks in colorectal surgery

  This study is testing a new method to check for leaks during colorectal cancer surgery to see if it helps reduce complications after the operation.

  Recruiting Nanchong Central Hospital · Nanchong, Sichuan · NCT06865638

• Evaluating a new device to prevent stoma creation after colorectal surgery

  This study is testing a new device to see if it can help prevent the need for a stoma after colorectal surgery in adults who are at risk of complications.

  Recruiting at 3 sites JSR Medical Co., Ltd. · Buffalo, New York and 2 other locations · NCT05826743

• Knife-assisted full-thickness resection for rectal lesions in a multicenter setting

  A multicenter study tests knife-assisted full-thickness resection (kFTR) to remove rectal lesions in adults and see how well it works and how safe it is.

  Recruiting University Hospital, Ghent · Ghent · NCT07923682

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.