Analyzing immune cells in children undergoing anesthesia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to characterize immune cells in pediatric patients aged 2 to 18 years who are undergoing general anesthesia and are expected to receive Rocuronium, a neuromuscular blocking agent. The study utilizes single-cell transcriptomic analysis to gain insights into the immune response during anesthesia, particularly in the context of potential drug allergies. By focusing on this specific patient population, the research seeks to enhance understanding of immune cell behavior in response to anesthesia and associated medications.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Pediatric patients between the ages of 2 and 18 undergoing general anesthesia and surgery using the neuromuscular blocker, rocuronium.

Exclusion Criteria:

* Patients who have received immunomodulators, immunosuppressants, etc.
* Patients with autoimmune diseases (rheumatoid arthritis, lupus, Behcet's disease, etc.)
* Patients who regularly take, or have taken within 4 weeks, medications that may affect the immune system (oral steroids, anti-inflammatories, etc.)
* Other cases where the Principal Investigator determines that it is difficult to conduct the study.

Where it's running

• Seoul National University Hospital
  Seoul, South Korea Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.