Cryocompression versus icepacks after total knee replacement

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This monocentric randomized controlled trial will compare postoperative cryocompression using a Game Ready device to standard icepacks in adults having primary total knee replacement. Participants who meet inclusion criteria will be randomized and receive the assigned cold therapy after surgery, with teams recording pain on a visual analogue scale, range of motion, knee circumference, and opioid consumption. The trial builds on a small RCT by Marinova et al. that found only short-term improvement in extension range of motion, so this study aims to provide more definitive data with fewer losses to follow-up. The study is conducted at Clinique des Cèdres in Échirolles and requires on-site visits and French-language communication.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* aged ≥18 years
* scheduled for primary TKR
* BMI \<40 kg/m2
* who signed the informed consent and are willing to comply with the protocol requirements based on the investigator's judgment
* affiliated with a social security scheme
* with an ability to answer questionnaires and to communicate freely in French.

Exclusion Criteria:

* underwent revision TKR
* underwent bilateral TKR
* who cannot comply with the protocol requirements based on the investigator's judgment
* that are pregnant or breastfeeding
* with protected status under articles L1121-6, LL121-8 and L1122-2 of the French Public Health Code

Where it's running

• Clinique des Cèdres
  Échirolles, France Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.