Clinical trial Recruiting at 1 site Observational Ages 100 and up

Centenarian cohort in Navarre to study aging and longevity

Official title: BIOANCIENT: Cohort of Centenarians in Navarra (1926-1927)

Run by Fundacion Miguel Servet · NCT07707297 · Data updated 2026-11-12

This study tests what factors help centenarians in Navarre stay healthier as they age and what might explain their exceptional longevity.

Quick facts

Study typeObservational
Ages100 Years and up
SexAll
Enrollment333 (estimated)
SponsorFundacion Miguel Servet
Academic / other
Locations1 site (Pamplona, Navarre)
StatusRecruiting
StartedFebruary 4, 2026
Main results expectedDecember 31, 2027
Study endsDecember 31, 2027
Registry record updatedJuly 16, 2026
Trial IDNCT07707297 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are residents of Navarre who are 100 years or older and in stable health without recent acute illness or hospitalization.

Probably not a fit

Individuals with active clinical decompensation, acute illness, or imminent end-of-life status may not benefit from participation.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational cohort study enrolling individuals aged 100 and older who reside in Navarre, Spain. It will collect clinical assessments, functional and cognitive measurements, and biological markers to explore how genetics, epigenetics, environment, and lifestyle contribute to extreme longevity. The goal is to identify determinants of healthy aging and to understand aging mechanisms in a real-world population. Data integration will combine biomedical data with lifestyle and environmental information to build a multi-dimensional view of aging trajectories. Results may inform strategies to promote healthy aging in the broader population.

Why it matters

Potential benefit: Findings could help identify factors that promote healthy aging and longevity, informing strategies to improve quality of life for older adults.

How similar studies have gone: Centenarian studies have provided insights into longevity, though intergenerational and multi-omics approaches remain an evolving area.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Individuals aged ≥100 years
* Residents of Navarre, Spain

Exclusion Criteria:

* Clinical decompensation within the last month, including hemodynamic instability, acute illness, or hospitalization;
* End-of-life condition, defined as a clinical state of irreversible deterioration with a life expectancy of days to weeks, as determined by a physician.

Where it's running

  • Navarrabiomed
    Pamplona, Navarre, Spain
    Recruiting

Study contacts

  • Principal investigator: Nicolas Martínez Velilla, MD and PhD — Navarrabiomed, Hospital Universitario de Navarra, IdisNa, Universidad Pública de Navarra
  • Study coordinator: Nicolás Martínez Velilla, MD and PhD
  • Email: nicolas.martinez.velilla@navarra.es
  • Phone: +34 848 422 287

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.