Sponsor or institution

Clinical trials and research at Vanderbilt-Ingram Cancer Center

• 44Clinical trials
• 1New in 30 days
• 2Countries

Newest trials

All recruiting trials (44)

• Cemiplimab with Quad Shot Radiation for Head and Neck Cutaneous Squamous Cell Carcinoma

  This study tests whether giving cemiplimab together with a short course of Quad Shot radiation can be safely delivered in several rounds to elderly or frail patients with head and neck skin cancer.

  Recruiting Early Phase 1 Vanderbilt-Ingram Cancer Center · St Louis, Missouri · NCT07869823

• Intrathecal Cytarabine and Hydrocortisone to Treat ICANS in NHL Patients Receiving CAR-T

  This trial tests whether giving cytarabine and hydrocortisone into the spine early after CAR-T therapy can reduce brain-related side effects in adults with non-Hodgkin lymphoma.

  Recruiting Phase 2 Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT07763210

• Casdatifan for refractory metastatic clear cell kidney cancer

  This pilot, first-in-human study tests whether taking casdatifan by mouth can help people with metastatic clear cell renal cell carcinoma that has not responded to prior therapies.

  Recruiting Phase 1 Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT07748988

• Targeted dual-imaging helper for head and neck cancer surgery

  This study tests whether using two imaging agents during surgery can help doctors see tumors and cancerous lymph nodes in adults with head and neck squamous cell carcinoma.

  Recruiting Phase 1 Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT07741643

• Intratumoral fluorescent nivolumab before surgery in head and neck cancer

  This study tests injecting fluorescently labeled nivolumab directly into head and neck tumors to see if it is safe and whether it reaches nearby lymph nodes before surgical removal.

  Recruiting Early Phase 1 Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT07741565

• Nemtabrutinib Plus Brexucabtagene Autoleucel (Brexu-Cel) in Relapsed or Refractory Mantle Cell Lymphoma

  This phase 2 trial tests whether adding nemtabrutinib to brexu-cel can help people whose mantle cell lymphoma has come back or not responded to prior treatment.

  Recruiting Phase 2 Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT07673367

• Bone density changes with anti-PD-1 immunotherapy

  This pilot will test if anti-PD-1 immunotherapy changes bone density in adults starting approved anti-PD-1 treatment for certain early-stage cancers.

  Recruiting Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT07555210

• Panitumumab-IRDye800 for guiding brain tumor surgery

  A tiny dose of panitumumab-IRDye800 is tested to see if it helps visualize brain tumors during surgery in adults.

  Recruiting Early Phase 1 Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT07493447

• Maintaining myeloma with less frequent daratumumab plus lenalidomide

  This phase 2 study tests a reduced-dosing schedule of daratumumab with lenalidomide to maintain remission in adults with multiple myeloma after stem cell transplant.

  Recruiting Phase 2 Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT07485647

• Nivolumab-IRDyE800CW imaging agent used before surgery in head and neck cancer

  This early-stage trial tests whether nivolumab labeled with IRDye800CW can safely be given before surgery to see if it helps image head and neck squamous cell carcinoma.

  Recruiting Phase 1 Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT07460765

• Using [18F]NOTA-ABY030 PET/CT to clarify indeterminate head and neck squamous cell carcinoma lesions

  This trial will test whether the new PET imaging agent [18F]NOTA-ABY030 is safe and can better detect unclear primary or metastatic lesions in adults with head and neck squamous cell carcinoma.

  Recruiting Phase 1 Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT07217028

• Fluorescent-labeled nivolumab (Nivo800) imaging for high-grade glioma surgery

  This trial tests whether a near-infrared fluorescent version of the immunotherapy drug nivolumab can be given before planned surgery to visualize drug distribution in adults with suspected high-grade glioma.

  Recruiting Early Phase 1 Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT07210632

• Darolutamide alone or with standard pre-surgery therapy for stage II–IIIA AR‑positive triple‑negative breast cancer.

  This trial will test whether adding darolutamide to standard pre-surgery chemo‑immunotherapy helps people with stage II–IIIA androgen receptor–positive triple‑negative breast cancer.

  Recruiting Phase 2 Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT07016399

• High-resolution PET-CT to visualize surgical tumor margins

  This will test whether a low-dose, high-resolution PET-CT scan of removed tumor tissue can help surgeons spot at-risk margins during surgery for adults with solid cancers such as head and neck squamous cell carcinoma.

  Recruiting Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT06915454

• PET imaging with [68Ga]Ga-ABY-025 to visualize HER2-positive and HER2-low tumors during HER2 therapy

  This trial will test whether a PET tracer called [68Ga]Ga-ABY-025 can better visualize tumors in adults with HER2-positive or HER2-low advanced cancers who are receiving HER2-targeted therapy.

  Recruiting Early Phase 1 Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT06828588

• Using a fluorescently labeled drug to improve surgery for head and neck cancer

  This study is testing a special version of a cancer drug to see if it can help doctors see tumors better during surgery for patients with head and neck cancer.

  Recruiting Phase 1 Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT06819228

• Registry and biorepository for clonal hematopoiesis and its effects on health

  This study is trying to understand how clonal hematopoiesis affects health, especially heart risks and blood cancers, by collecting information and samples from patients with this condition or those at higher risk.

  Recruiting Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT06701214

• Understanding the long-term effects of sarcoma on survivors

  This study is trying to understand how surviving sarcoma affects people's health and wellbeing over time by looking at their activity levels, health data, and personal experiences.

  Recruiting Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT06482957

• Combining eltanexor and venetoclax for treating relapsed or refractory blood cancers

  This study is testing a new combination of two medications, eltanexor and venetoclax, to see if they can help people with relapsed or hard-to-treat blood cancers like myelodysplastic syndrome and acute myeloid leukemia.

  Recruiting at 2 sites Phase 1 Vanderbilt-Ingram Cancer Center · Memphis, Tennessee and 1 other locations · NCT06399640

• Combining total body irradiation with chemotherapy and immunotherapy for extensive stage lung cancer

  This study is testing if adding total body radiation to standard chemotherapy and immunotherapy can help people with advanced small cell lung cancer live longer and feel better.

  Recruiting Phase 1/2 Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT06110572

• Comparing two methods for obtaining lung cancer tissue samples

  This study is testing which method, cryobiopsy or EBUS-TBNA, is better at getting enough lung cancer tissue samples for testing in patients.

  Recruiting Phase 4 Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT06105801

• Surgical removal followed by targeted radiation therapy for neuroendocrine tumors

  This study is testing if surgery followed by a special radioactive treatment can help people with certain types of cancer that have spread to the liver.

  Recruiting Phase 4 Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT06016855

• Assessing tumor hypoxia using MRI to improve radiation therapy

  This study is testing if special MRI scans can help doctors understand and improve radiation treatment for patients with head and neck cancer or brain metastases by looking at how much oxygen their tumors are getting.

  Recruiting Early Phase 1 Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT05996432

• Using dual imaging techniques to detect head and neck cancer

  This study is testing two new imaging techniques to see if they can better detect head and neck cancer in patients before surgery.

  Recruiting Phase 1 Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT05945875

• Using neratinib before surgery for HER2-mutated lobular breast cancers

  This study is testing if adding a new drug called neratinib to standard treatment can help people with HER2-mutated lobular breast cancer before they have surgery.

  Recruiting at 2 sites Phase 2 Vanderbilt-Ingram Cancer Center · Atlanta, Georgia and 4 other locations · NCT05919108

• Using a radioactive drug to find cancer spread in head and neck patients

  This study is testing a new radioactive drug to see if it can help doctors find cancer spread in the lymph nodes of patients with head and neck cancer before surgery.

  Recruiting Phase 1 Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT05901545

• Combination of pBI-11 and TA-HPV vaccines with pembrolizumab for advanced oropharyngeal cancer

  This study is testing a new combination of two vaccines and a medication to see if it can help people with advanced oropharyngeal cancer that is linked to HPV feel better and live longer.

  Recruiting at 2 sites Phase 2 Vanderbilt-Ingram Cancer Center · Birmingham, Alabama and 1 other locations · NCT05799144

• Using blood tests to guide chemotherapy changes in metastatic breast cancer

  This study is testing if using blood tests to track cancer DNA can help doctors change chemotherapy treatments faster for people with metastatic triple-negative breast cancer.

  Recruiting Phase 2 Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT05770531

• Using a new imaging agent to detect metastases in head and neck cancer

  This study is testing a new imaging agent to see if it can help find hidden cancer spread in people with head and neck cancer better than current methods.

  Recruiting Phase 1 Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT05747625

• Investigating the genetics of appendix cancer

  This study is trying to find out how genetics might play a role in appendix cancer by following adults with the disease for up to six years.

  Recruiting Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT05734430

• Evaluating chemotherapy versus endocrine therapy for hormone receptor-positive metastatic breast cancer

  This study is testing whether a chemotherapy drug called capecitabine works better than hormone therapy for people with hormone receptor-positive metastatic breast cancer who have already tried other treatments.

  Recruiting at 4 sites Phase 2 Vanderbilt-Ingram Cancer Center · Birmingham, Alabama and 3 other locations · NCT05693766

• Combining adaptive radiation therapy with immunotherapy for advanced lung cancer treatment

  This study is testing a new way of giving radiation therapy along with immunotherapy to see if it helps people with advanced lung cancer feel better and live longer.

  Recruiting Phase 1/2 Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT05501665

• Genetic testing to choose the best treatment for advanced kidney cancer

  This study is testing if using genetic testing to pick the best treatment can help people with advanced kidney cancer respond better to either a combination of immunotherapy drugs or a mix of immunotherapy and targeted therapy.

  Recruiting at 6 sites Phase 2 Vanderbilt-Ingram Cancer Center · Duarte, California and 5 other locations · NCT05361720

• Study on preserving fertility in young adults with colorectal cancer

  This study is testing how colorectal cancer and its treatments affect fertility and sexual health in young adults aged 18 to 49.

  Recruiting Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT05239338

• Using gabapentin and ketamine to manage pain in head and neck cancer patients

  This study is testing a combination of gabapentin and ketamine to see if it can safely help manage pain for patients with advanced head and neck cancer who are receiving treatment.

  Recruiting Phase 1/2 Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT05156060

• Shorter radiation treatment followed by surgery for soft tissue sarcomas

  This study is testing if a shorter radiation treatment followed by surgery can help people with soft tissue sarcomas while causing fewer side effects.

  Recruiting Phase 2 Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT04506008

• Improving recovery after surgery for extremity sarcoma

  This study is testing a new recovery plan for people having surgery for extremity sarcoma to see if it helps them manage pain better and recover faster without using narcotics.

  Recruiting Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT04461171

• Testing new drug combinations for myelodysplastic/myeloproliferative neoplasms

  This study is testing new combinations of medications for people with myelodysplastic/myeloproliferative neoplasms to see if they can improve treatment outcomes and safety.

  Recruiting at 4 sites Phase 1/2 Vanderbilt-Ingram Cancer Center · Tampa, Florida and 3 other locations · NCT04061421

• Evaluating health outcomes in retinoblastoma patients after treatment

  This study looks at the health and vision outcomes of people who have been treated for retinoblastoma to see how they are doing over time.

  Recruiting at 11 sites Vanderbilt-Ingram Cancer Center · Chicago, Illinois and 10 other locations · NCT03932786

• Registry for individuals interested in inherited cancer predisposition

  This study is looking for people who want to learn more about inherited cancer risks and participate in research to help improve understanding and education about cancer genetics.

  Recruiting Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT03231891

• Collecting and studying bio-specimens from melanoma patients

  This study is collecting tissue and blood samples from melanoma patients to learn more about the disease and improve future treatments.

  Recruiting Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT01205815

• Collecting tissue samples from women with or without breast cancer

  This study is collecting tissue, blood, and urine samples from women with and without breast cancer to create a database that helps researchers understand how breast cancer develops and progresses.

  Recruiting Vanderbilt-Ingram Cancer Center · Nashville, Tennessee · NCT00899301

• Identifying cancer predictors in high-risk lung cancer patients

  This study is trying to find out if certain biological markers in blood and other samples can help predict lung cancer in people who are at high risk.

  Recruiting at 2 sites Vanderbilt-Ingram Cancer Center · Nashville, Tennessee and 1 other locations · NCT00898313

• Collecting and analyzing lung tissue samples from patients with non-small cell lung cancer

  This study is trying to see if analyzing lung tissue samples from patients with non-small cell lung cancer can help predict how their tumors will behave and how well they might do after treatment.

  Recruiting Vanderbilt-Ingram Cancer Center · Nashville, Tennessee and 2 other locations · NCT00897117

Quick answers

How many clinical trials run by Vanderbilt-Ingram Cancer Center are recruiting right now?

44, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in United States (44 trials), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 10, Phase 1: 9, Early Phase 1: 6, Phase 1/2: 4. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →