Identifying cancer predictors in high-risk lung cancer patients
Molecular Predictors of Lung Cancer Behavior
This study is trying to find out if certain biological markers in blood and other samples can help predict lung cancer in people who are at high risk.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 4000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Vanderbilt-Ingram Cancer Center Academic / other |
| Locations | 2 sites (Nashville, Tennessee and 1 other locations) |
| Trial ID | NCT00898313 on ClinicalTrials.gov |
What this trial studies
This observational study aims to identify molecular predictors of lung cancer in patients at high risk by analyzing various biological samples, including blood, urine, sputum, and lung tissue. The research focuses on evaluating DNA, RNA, and protein abnormalities in lung lesions using advanced techniques such as comparative genomic hybridization and proteomic profiling. By employing less invasive methods, the study seeks to improve the diagnosis and staging of both pre-invasive and invasive lung cancer lesions.
Who should consider this trial
Good fit: Ideal candidates for this study are adults referred for evaluation of signs or symptoms of lung cancer at participating medical centers.
Not a fit: Patients who are unable to provide informed consent, minors, or pregnant women will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to earlier detection and better management of lung cancer in high-risk patients.
How similar studies have performed: Other studies have shown promise in using molecular predictors for cancer diagnosis, making this approach both relevant and potentially impactful.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: -All adults referred to Vanderbilt Medical Center, Veterans Administration Medical Center, St. Thomas Hospital and Meharry Medical Center for evaluation of signs or symptoms of lung cancer. Exclusion Criteria: * Inability to provide informed consent * Minors * Pregnant women
Where this trial is running
Nashville, Tennessee and 1 other locations
- Vanderbilt-Ingram Cancer Center — Nashville, Tennessee, United States (Recruiting)
- Veterans Affairs Medical Center - Nashville — Nashville, Tennessee, United States (Recruiting)
Study contacts
- Study coordinator: Vanderbilt Ingram Clinical Trials Information Program
- Phone: 1-800-811-8480
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.