Sponsor or institution

Clinical trials and research at University of South Dakota

• 16NIH research projects

NIH-funded research (16)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Boosting the cell cleanup system to protect against aging and Alzheimer's

  Researchers will see whether changing a tiny chemical switch on the cell's protein-cleaning machinery helps prevent aging-related damage and Alzheimer's changes in the brain and heart.

  NIH research University of South Dakota · Vermillion, United States · NIH-11297483

• Programmable stem cells to improve survival and therapy in damaged tissues

  Researchers are developing engineered mesenchymal stem cells that can sense stress in damaged tissues and respond with protective signals to boost healing.

  NIH research University of South Dakota · Vermillion, United States · NIH-11267049

• Understanding how heart cells control protein disposal to prevent heart failure

  A research project from the University of South Dakota aims to learn how the heart’s protein disposal system works during ischemic heart disease to help prevent heart failure.

  NIH research University of South Dakota · Vermillion, United States · NIH-11248064

• Mobile web app to increase cervical cancer screening for Yankton Sioux women

  A culturally tailored mobile web app will send personalized messages to help Yankton Sioux women ages 25–65 stay up to date with cervical cancer screening.

  NIH research University of South Dakota · Vermillion, United States · NIH-11170413

• Using brain growth signals to help memory and thinking

  Testing lab-designed versions of the hormone erythropoietin that keep its brain-helping effects but not the blood effects, to help people with memory and attention problems.

  NIH research University of South Dakota · Vermillion, United States · NIH-11127435

• South Dakota INBRE: Growing Biomedical Research in SD

  A statewide program builds biomedical research capacity in South Dakota by supporting training, collaboration, and shared core resources across universities.

  NIH research University of South Dakota · Vermillion, United States · NIH-11093670

• Targeting HIV reservoirs in the brain to improve treatment outcomes

  This study is looking for new ways to help people with HIV by targeting hidden spots in the brain where the virus can still hide, even when they're on treatment, and it focuses on understanding how certain proteins can help in this process.

  NIH research University of South Dakota · Vermillion, United States · NIH-11081715

• Using smart nanoparticles to deliver a natural cancer-fighting drug for metastatic colorectal cancer.

  This study is testing a new way to deliver a natural anti-cancer drug directly to metastatic colorectal cancer cells using tiny particles, which could make the treatment work better and cause fewer side effects for patients with advanced CRC.

  NIH research University of South Dakota · Vermillion, United States · NIH-11077358

• How cockroaches spread Salmonella bacteria

  This study looks at how German cockroaches can spread Salmonella bacteria, which can make people very sick, by exploring how the bacteria grow inside the cockroaches' bodies.

  NIH research University of South Dakota · Vermillion, United States · NIH-10973607

• A mobile app to help Indigenous women get screened for cervical cancer

  This study is testing a new mobile app designed to help Indigenous women, especially those in the Yankton Sioux Tribe, get regular cervical cancer screenings by providing helpful information and reminders, and it will see how well this app works compared to regular printed materials.

  NIH research University of South Dakota · Vermillion, United States · NIH-10843553

• Training diverse biomedical scientists at the University of South Dakota

  The G-RISE program at the University of South Dakota is designed to help a diverse group of students, especially those from underrepresented backgrounds, become successful scientists by combining classroom learning with real research experience and personalized support from mentors.

  NIH research University of South Dakota · Vermillion, United States · NIH-10829830

• Understanding the links between PTSD, alcohol use, and relationship conflicts in veterans

  This study is looking at how PTSD and alcohol use can lead to conflicts in relationships for veterans, and it will help them learn new ways to manage their feelings and behaviors over two years while tracking their daily experiences.

  NIH research University of South Dakota · Vermillion, United States · NIH-10827940

• Investigating how a specific gene affects social behavior in children with autism.

  This study is looking at how a specific gene might affect social behavior in kids with autism by exploring how certain brain cells work, using mice that show similar traits, to help find new ways to support children with autism in their social interactions.

  NIH research University of South Dakota · Vermillion, United States · NIH-10725205

• How early exposure to alcohol affects genes and behavior

  This study is looking at how drinking alcohol during pregnancy affects brain development and behavior, using zebrafish to learn more about the possible genetic factors involved, which could help us find ways to support people with Fetal Alcohol Spectrum Disorder (FASD).

  NIH research University of South Dakota · Vermillion, United States · NIH-10686974

• Understanding how proteasome regulation affects heart health

  This study is looking at how certain proteins in the heart can be changed to help improve heart function, with the goal of finding new treatments for people with heart disease.

  NIH research University of South Dakota · Vermillion, United States · NIH-10627948

• Understanding how stress affects men and women differently in the brain

  This study is looking at how men and women's brains react differently to stress, which could help us understand why women might face more emotional challenges and men might be at greater risk for suicide, with the hope of finding better treatments for stress-related mental health problems.

  NIH research University of South Dakota · Vermillion, United States · NIH-10291077

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