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Clinical trials and research at University of Siena

• 8Clinical trials
• 22Countries

Newest trials

All recruiting trials (8)

• Restoring Cervical Lymphatic Drainage in Alzheimer’s Disease

  A small study tests whether a minimally invasive surgery to improve cervical lymphatic drainage can affect biomarkers, brain imaging, and cognition in people with Alzheimer's who can’t access other disease-modifying therapies.

  Recruiting University of Siena · Siena, Tuscany · NCT07854327

• Comparing root canal sealers and filling techniques for healing after treatment

  This will test whether two sealers (AH Plus and NeoSealer Flo) and two obturation techniques (continuous wave and single cone) lead to better x‑ray healing in adults needing root canal treatment.

  Recruiting University of Siena · Madrid, Spain · NCT07019298

• Postoperative pain after root canal filling with bioceramic or resin-based sealers.

  This project will see if using bioceramic versus resin-based sealers for root canal fillings changes short-term pain in adults with pulpitis, pulp necrosis, or previously treated teeth.

  Recruiting University of Siena · Madrid · NCT07018284

• Comparing two types of ultrasonic devices for treating gum disease

  This study is testing which type of ultrasonic device, piezoelectric or magnetostrictive, works better for treating gum disease and how patients feel about the treatment.

  Recruiting University of Siena · Siena, SI · NCT06934291

• Gene editing to correct common MECP2 mutations in Rett syndrome

  This project will test CRISPR/Cas9 delivered with AAV to correct common MECP2 mutations in females with Rett syndrome using lab and animal work.

  Recruiting University of Siena · Siena, Siena · NCT05740761

• Registry for hereditary autoinflammatory diseases

  This study is collecting information about hereditary autoinflammatory diseases to see how they affect patients of different ages and genders, with the goal of improving treatment and care for everyone affected.

  Recruiting at 112 sites University of Siena · Algiers and 111 other locations · NCT05200715

• Comparing two types of lymphadenectomy after chemotherapy for stomach cancer

  This study is testing whether a more extensive type of surgery for stomach cancer after chemotherapy can help patients do better than the standard surgery.

  Recruiting Phase 3 University of Siena · Siena · NCT03961373

• Continuous versus intermittent IV furosemide for acute heart failure

  This trial tests whether giving furosemide as a continuous IV infusion or as intermittent IV boluses works better for adults hospitalized with acute decompensated heart failure.

  Recruiting at 4 sites University of Siena · Chioggia, Venezia and 3 other locations · NCT02638142

Quick answers

How many clinical trials run by University of Siena are recruiting right now?

8, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 22 countries. The most sites are in Italy (6 trials), Spain (3 trials), Algeria (1 trial), Australia (1 trial), Belgium (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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