Comparing two types of ultrasonic devices for treating gum disease
Official title: Clinical and Patient-Centered Outcomes of Full-Mouth Ultrasonic Debridement for Periodontitis: A Randomized Controlled Trial Comparing Piezoelectric and Magnetostrictive Devices
Run by University of Siena · NCT06934291 · Data updated 2026-11-12
This study is testing which type of ultrasonic device, piezoelectric or magnetostrictive, works better for treating gum disease and how patients feel about the treatment.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 52 (estimated) |
| Sponsor | University of Siena Academic / other |
| Locations | 1 site (Siena, SI) |
| Status | Recruiting |
| Started | March 31, 2025 |
| Main results expected | October 2025 |
| Study ends | October 2025 |
| Registry record updated | September 10, 2025 |
| Trial ID | NCT06934291 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults over 18 years old diagnosed with stage 1 or 2 periodontitis and without systemic chronic diseases.
✕Probably not a fit
Patients on anticoagulant therapy or who have received antibiotic treatment within three months prior to screening may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study compares the clinical and psychological outcomes of full-mouth ultrasonic debridement for periodontitis using either piezoelectric or magnetostrictive devices. Patients diagnosed with periodontitis will undergo a thorough periodontal assessment before being randomly assigned to one of the two treatment groups. Following treatment, patient perceptions will be recorded, and a follow-up evaluation will occur three months later to assess the effectiveness of the interventions. The goal is to determine which device yields better outcomes for patients.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment options for patients with periodontitis, enhancing both clinical and psychological outcomes.
How similar studies have gone: Other studies have shown varying success with ultrasonic debridement techniques, but this specific comparison of devices is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * \>18 years * periodontitis of stage 1 and 2 * absence of systemic chronic disease Exclusion Criteria: * anticoagulants treatment * antibiotic treatment 3 months before the screening visit
Where it's running
-
Aous
Siena, Si, Italy Recruiting
Study contacts
- Study coordinator: Nicola Discepoli, DDS, MSc
- Email: nicola.discepoli2@unisi.it
- Phone: 3395256148
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
HbA1c screening in dental care to guide primary care referral for adults with advanced periodontitis
This study tests whether a quick HbA1c test in dental clinics can find elevated blood sugar in adults with advanced periodontitis and help refer them to their primary care doctor.
-
Masticatory Performance in Adults with Periodontitis
This study tests whether chewing performance correlates with how severe periodontitis is in adults who have the condition.
-
Probiotics with or without vitamin B12 added to non-surgical treatment for advanced periodontitis
This study will see if taking a probiotic lozenge alone or together with vitamin B12 during non-surgical periodontal treatment changes the oral microbiome and helps adults with Stage III or IV periodontitis.
-
3-month liquid platelet-rich fibrin treatment used during deep cleaning for stage II–IV periodontitis
This 3-month test will see if flushing diseased gum pockets with your own liquid platelet-rich fibrin after deep cleaning helps healing for people with stage II–IV periodontitis.
-
Enamel matrix derivatives to thicken gum tissue around dental implants
We will test whether applying enamel matrix derivatives under the gum flap during implant uncovering makes gum tissue thicker and increases the width of keratinized mucosa in adults getting dental implants.
-
Non-surgical treatment for gum disease using chitosan and enamel matrix
This study is testing a new non-surgical treatment using a special brush and gel to help people with advanced gum disease and specific tooth issues.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.