Sponsor or institution
Clinical trials and research at University of North Texas
As of November 12, 2026, Find a Trial lists 36 NIH-funded research projects at this institution, with $11.6 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 36NIH research projects
NIH-funded research (36)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Cataracts and Work Exposures in Denmark
A large Danish study will look at whether job-related exposures, both chemical and non-chemical, are linked to developing cataracts.
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New approach to find noninvasive brain networks that predict epilepsy after brain injury
A study aims to identify noninvasive brain biomarkers that can forecast epileptogenesis after brain injury by linking MRI network patterns with EEG signals.
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Off-the-shelf ADC-NK cell therapy platform for cancer and immune diseases
A universal, ready-to-use natural killer cell therapy armed with antibody-drug conjugates is being developed to target cancers and other diseases.
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New and better ways to measure kids' exposure to air pollution and traffic
This project looks at how traffic-related air pollution and green space around homes may affect cancer risk in children and uses advanced exposure measurements to better understand these links.
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Can a single model work for high-resolution 3D genome structure using generalizable methods
A grantfunds researchers to create high-resolution 3D genome models that can work across different cell types using advanced algorithms and machine learning.
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How tissue stiffness and stretching affect nanoparticle delivery in cancer and other diseases
This grant studies how the physical properties of tissues, like stiffness and stretch, influence how nanoparticles are taken up by cancer-related cells to improve future therapies.
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Enzyme‑activated peptides to target drug‑resistant triple‑negative breast cancer
This project uses enzyme‑activated peptides that form tiny fibers inside triple‑negative and drug‑resistant breast cancer cells to help kill them.
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New high-resolution ultrasound imaging system for small animals
A new Vevo F2 LT ultrasound scanner will be installed at a university campus to enable real-time, non-invasive heart and tumor imaging in small animals.
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GPU-powered computer system to accelerate biomedical AI and big data work
A high-performance GPU server is being funded to help researchers and students at UNT run AI-based biomedical analyses more quickly.
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Advanced AI tools to connect big biomedical data for better genes and personalized care
A researcher team plans to build open-source computer methods that combine genomics, EHRs, and other health data to better predict patient outcomes and find new drug uses.
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Targeted mild cooling to prevent hearing loss
This project develops a non-invasive, targeted mild cooling approach to help adults at risk of hearing loss from loud noise or certain medical treatments.
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Synthetic sugar-like molecules to regulate platelet production
Aims to test synthetic molecules that mimic natural sugars to help the body make healthy platelets.
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How tissue stiffness and stretch change nanoparticle entry into lung and blood vessel cells
This work looks at how stretching and stiffness in lung and blood vessel tissues change the way tiny drug-carrying nanoparticles get into cells, with the goal of improving treatments for cancer and lung or vascular disease patients.
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Investigating heart damage caused by cancer drugs using advanced human models
This study is looking at how certain cancer drugs called tyrosine kinase inhibitors might affect your heart, using a new method that combines human heart tissue and advanced technology to help find any heart problems early on, making cancer treatments safer for everyone.
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Enzyme-activated peptides to target drug-resistant breast cancer
This work develops enzyme-triggered peptides that aim to kill triple-negative and drug-resistant breast cancer cells.
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How Tissue Stiffness Affects Nanoparticle Medicines for Diseases like Cancer
This research explores how the stiffness and movement of body tissues change how tiny medicine particles get into cells, aiming to make treatments for conditions like cancer more effective.
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Investigating synthetic mimics of glycosaminoglycans to regulate blood cell production.
This study is looking at how special synthetic compounds can help boost the production of platelets, which are important for stopping bleeding, and it's aimed at finding new ways to improve blood clotting for people who might need it.
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Understanding brain signals to predict epilepsy
This research aims to understand specific brain signals that could help predict when epilepsy might develop, especially for people who don't respond to current treatments.
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New method to target drug-resistant breast cancers using enzyme-stimulated peptides
This study is exploring new treatments for triple-negative breast cancer by using specially designed molecules to target a specific enzyme, aiming to stop the cancer cells from growing and help patients who often struggle with standard therapies.
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Using advanced computer models to understand genes and personalize medicine
This work creates new computer tools to combine different types of health information, like genetic data and medical records, to better understand diseases and find new treatments for patients.
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Understanding how proteins regulate potassium channels involved in epilepsy
This study is looking at how certain proteins affect potassium channels in nerve cells, which are important for conditions like epilepsy, using tiny worms to help us learn more about these channels and how they might relate to human brain disorders.
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Creating new cellular behaviors using genetic sensors and circuits
This study is working on creating smart genetic tools that can react to different chemical signals in the body, which could help improve tests and treatments for various health issues, making life easier for patients.
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Targeting drug-resistant breast cancers using enzyme-stimulating peptides
This study is exploring a new treatment for triple-negative breast cancer that uses specially designed molecules to help stop the cancer cells from growing, and if successful, it could offer hope for patients who currently have limited options.
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How mechanical properties of tissues affect nanoparticle delivery to cells
This study is looking at how the stiffness and stretch of lung and blood vessel tissues affect how tiny particles used in medicine get into cells, with the hope of making these particles work better for delivering treatments.
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Improving family-school partnerships for young children with communication challenges
This study is all about helping teachers and parents work together better to support young children who have trouble with social communication, so they can learn and grow in preschool.
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Identifying brain networks to predict epilepsy development
This study is looking at how specific brain connections might lead to epilepsy before seizures start, using animal models to find out more about these early changes, with the hope of creating new treatments that could help people with epilepsy.
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Using advanced data analysis to find new treatments for Alzheimer's disease
This study is looking for new ways to find better treatments for Alzheimer's and related dementias by using advanced computer techniques to combine information about drugs and diseases, hoping to speed up the process of discovering effective options for patients like you.
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Improving remote breathalyzer methods for monitoring alcohol use
This study is working on improving breathalyzers that check alcohol levels in your breath, so they can give more accurate readings throughout the day, even when no one is watching, helping doctors and researchers better support people who are trying to manage their alcohol use.
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Understanding factors that regulate von Willebrand Factor levels
This study is looking at how certain genes affect the amount of a protein called von Willebrand Factor, which is important for blood clotting, and it's designed for people interested in understanding conditions like von Willebrand disease and blood clotting issues.
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Using advanced data analysis to identify genes and drug responses related to diseases.
This study is working on new computer tools that look at a lot of biological information to find out which genes are linked to diseases and how different patients might respond to treatments, all to help create more personalized care for everyone.
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Investigating how small RNA affects genetically modified mosquitoes
This study is looking at how tiny RNA molecules in genetically modified mosquitoes might affect the genes that help control mosquito populations and fight diseases, with the goal of finding better ways to manage diseases spread by these insects.
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Investigating how air pollution affects obesity through gut health and fat tissue.
This study is looking at how air pollution from traffic might be linked to obesity by affecting the bacteria in our gut and how our body handles fat, with the goal of finding new ways to help people living in polluted cities stay healthy.
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Exploring a new technique to help people with Posttraumatic Stress Disorder by focusing on positive memories.
This study is testing a new way to help people with PTSD feel better by focusing on their positive memories, and it's for anyone looking for support in managing their symptoms.
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Investigating how NOTCH signaling affects heart development in a congenital heart disease.
This study is looking at how a specific signaling process in cells might help us understand and improve heart development in babies with hypoplastic left heart syndrome (HLHS) by creating tiny heart models from stem cells.
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Developing a new model to study optic nerve damage in glaucoma
This study is looking at how high pressure in the eye affects the optic nerve and can lead to vision loss in people with glaucoma, with the goal of finding better ways to treat the condition.
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How aortic valve function and heart devices affect blood transport in older adults with valve disease
This study is looking at how the movement of the aortic valve and the use of heart pumps (LVADs) affect the way bad cholesterol (LDL) moves around the heart, which is important for understanding and treating calcific aortic valve disease.
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