Sponsor or institution
Clinical trials and research at Texas A&m University Health Science Ctr
As of November 12, 2026, Find a Trial lists 196 NIH-funded research projects at this institution, with $82.7 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 196NIH research projects
NIH-funded research (newest 40 of 196)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
-
Dose-Dependent Brain Wire Modulation with Light Ultrasound in Deep White Matter
A small early study tests whether gentle, noninvasive ultrasound can change how deep brain white matter tracts work in healthy adults.
-
Automated self-acceptance training plus ketamine to extend antidepressant benefits
A study tests whether adding a quick computerized self-positivity training after ketamine can prolong relief from depression for people seeking ketamine treatment.
-
Ultrasound-guided brain circuit targets for treatment-resistant depression
This grant tests whether focused ultrasound can safely and reversibly adjust brain circuits linked to negative mood in people with treatment-resistant depression.
-
Back-Support Exoskeletons to Reduce Low Back Pain in Commercial Fishermen
A real-world trial will test whether wearable back-support exoskeletons can lower back pain and fatigue for commercial fishers on their boats.
-
Esophageal cancer start and immune changes
Researchers are studying how a specific cell type appears early in esophageal cancer and how it changes the surrounding immune environment, aiming to stop cancer before it grows.
-
Cholinergic Dysregulation and Cognitive Flexibility in Cocaine Use Disorder
A research study explores how cocaine changes brain signaling to affect flexible thinking and decision-making in people with cocaine use disorder.
-
Understanding how fat signals and cell signals drive abnormal bone formation after injury or genetic conditions
A study to learn how a leptin-related signaling pathway affects the fate of mesenchymal cells that form bone in places they shouldn’t, with the goal of finding ways to prevent painful, abnormal bone growth.
-
New beta-adrenergic signaling pathway links chronic stress to high blood pressure
A new study will look at how stress hormones influence immune cells to raise blood pressure, with people who have chronic stress as a potential focus for future therapies.
-
Endothelin-1 and retinal blood flow in early diabetes
A study in adults with brittle diabetes will look at how the tiny blood vessels in the retina respond to a molecule called endothelin-1 to understand why vision can be affected early in the disease.
-
Paternal e-cigarette exposure and its effect on blood clots
This grant studies whether a father’s use of e-cigarettes or vaping products before conception can affect his children and increase the risk of blood clots in the future.
-
Striatal Signaling Mechanisms in Parkinson’s Disease
A research project at Texas A&M University Health Science Center is exploring how brain signaling in the striatum contributes to Parkinson’s disease and whether new targets could lead to better treatments.
-
iPSC-derived EV therapy for dry mouth in Sjögren's syndrome or after head-and-neck radiation
A new treatment using tiny particles shed by lab-made stem cells could help restore saliva in people with Sjögren’s syndrome or after head-and-neck radiation.
-
Understanding and stopping abnormal bone growth after injury or genetic disease
A study to understand why bones grow where they shouldn’t after injuries or in certain genetic conditions, with the aim of finding ways to stop or treat it.
-
Novel hydrophilic neurosteroids to stop benzodiazepine-resistant seizures after nerve agent exposure
This grant aims to develop water-friendly neurosteroids that could prevent ongoing seizures and brain damage after nerve agent exposure, helping people who suffer organophosphate poisoning.
-
Epigenetic changes in aging brain support stroke recovery in aging women
This project explores how aging-related brain cells, especially astrocytes, respond after a stroke in older women and how hormones and epigenetic changes influence recovery and dementia risk.
-
Protecting the brain after stroke by targeting the gut with IGF-1
This project tests whether targeting the gut and the blood-gut barrier with IGF-1 can reduce brain damage and long-term memory and mood problems after ischemic stroke, particularly in older postmenopausal women.
-
Muscle’s role in fighting infection and managing energy
This grant studies how muscle tissue helps control infection by coordinating energy use and the immune response, aiming to reveal new ways muscles influence susceptibility to bacterial infections.
-
Understanding how GPCR regulators (RGS) control platelet function
Researchers are studying how specific regulators called RGS proteins affect how platelets respond, which could influence clotting in conditions like sepsis.
-
Metabolic Rescue Approach for Heart Failure
This project looks at a new metabolic mechanism that could help the heart regain energy and function in people with heart failure.
-
Genetics of anxiety disorders: how genes influence risk and treatment need
This NIH grant looks at how our genes influence anxiety disorders like generalized anxiety and panic, with findings that could lead to better risk prediction and new treatments.
-
Understanding how age affects mitochondrial function in astrocytes after spinal cord injury
This grant explores how aging changes mitochondria in brain-supporting cells after spinal cord injury and what that means for recovery.
-
Mesenchymal Stem Cell–Derived Vesicles to Help Traumatic Brain Injury
Aims to test a therapy made from stem-cell–derived vesicles given as an intranasal spray to improve brain function after traumatic brain injury in mice, focusing on both early and later treatment windows.
-
Female-specific trigeminal dynorphin role in TMD and migraine overlap
This grant studies why women with jaw pain (TMD) often have migraines and looks for female-focused targets to treat both conditions.
-
Pediatric toxoplasmosis: 3D-printed, dose-flexible treatments for children and adults
A new 3D-printed, adjustable-dose treatment approach for toxoplasmosis could make pediatric and patient-specific therapy safer, affordable, and easier to administer.
-
How a gut bacterium’s secret system may harm the colon and spread
Researchers are looking at how a protein released by the gut bacterium Streptococcus gallolyticus can change colon cells and help the bacteria cause bloodstream infections in people with or at risk for colorectal cancer.
-
GTPase regulator controls regenerative capacity in mouse teeth
A gene regulator that controls how stem cells in teeth grow back and repair themselves in mice could inform regenerative dental therapies for people.
-
Cholinergic Signals in Striatal Brain Circuits and Alcohol Use
This NIH grant explores how acetylcholine signaling in a key brain area may influence alcohol-seeking and drinking, with potential to guide new therapies for alcohol use disorder.
-
3D-printed flexible-dose HIV medicine for children
Making 3D-printed, dose-adjustable HIV combination medicines so children can get the right dose more easily.
-
Calcium-Dependent Self-Regulation of Vasopressin Neurons in Heart Failure (Rodent Model)
Researchers will study how brain cells that release vasopressin control their own activity and how this changes in a rodent model of heart failure.
-
How brain stem cells grow and organize in the developing mouse brain
Researchers study how neural stem cells in a developing mouse brain multiply, differentiate, and arrange themselves to form the cortex, which could help understand developmental disabilities
-
A shortened GLI1 protein and tiny RNA signals linked to breast cancer spread to the brain
This project looks at whether a shortened form of the GLI1 protein and certain microRNAs help breast cancer cells move to and grow in the brain.
-
Understanding how heat affects platelets and clotting
Researchers are studying how high body temperature may change how platelets work and whether that could raise the risk of dangerous clotting in people like firefighters.
-
LYFE-III: Scaling a culturally tailored online program to support Latino families
A family-based online program for Latino households aims to reduce youth mental health problems by delivering culturally adapted strategies.
-
Acquiring a high-tech slide scanner to boost tissue imaging at a university core lab
A core imaging lab at Texas A&M University aims to purchase a VS200 slide scanner with automation and structured illumination to speed up high-throughput tissue imaging for diverse cancer and cardiovascular research.
-
Stem cell “cell-drones” to help heal damaged hearts
This project creates engineered stem-cell nanovesicles called “cell-drones” to help hearts recover after a heart attack.
-
Brain circuit changes linked to alcohol relapse
Looks at whether changes in small groups of brain cells in a region called the dorsomedial striatum drive relapse and whether extinction-like training can reduce alcohol seeking in people with alcohol use disorder.
-
MINFLUX 3D Microscope for ultra-precise cellular imaging
A high-precision 3D microscope is being funded to help researchers study single molecules and cell processes at nanometer scales.
-
Oxytocin Helps Sleep Apnea Patients Handle Opioid Drowsiness Better
Aims to understand why sleep apnea makes opioids more dangerous by studying oxytocin’s role in protecting breathing, with the goal of safer pain relief for patients.
-
Stopping RET-driven breast cancer spread to the brain
This project looks at whether blocking the RET protein can slow or stop breast cancer that has spread to the brain.
-
How epigenetics guide the heart as it forms before birth
This project looks at how TET proteins that change DNA markings help the heart form in embryos and whether a mother's metabolism affects that process.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.