Sponsor or institution
Clinical trials and research at Research Triangle Institute
As of November 12, 2026, Find a Trial lists 246 NIH-funded research projects at this institution, with $726.6 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 246NIH research projects
NIH-funded research (newest 40 of 246)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Improving engagement and retention in the All of Us Research Program for children and youth.
This study is all about making online experiences better for kids and teens involved in the All of Us Research Program by listening to their ideas and working together to create new tools that fit their needs.
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Improving population health and preventing disease across the life course
This study is looking at how different factors influence pregnancy and child development to help improve health for families, especially for couples trying to conceive, pregnant women, and young children.
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Improving data resources for sickle cell disease management
This study is working to make it easier for people with sickle cell disease to share and access important health information, so they can have a better experience and help researchers find new ways to improve their care.
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Improving colorectal cancer screening and follow-up care.
This study is working to help more people get screened for colorectal cancer and receive the follow-up care they need, especially those who haven't been screened much before, so that everyone can have better access to important health checks and improve their overall health.
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BioData Catalyst Data Management Core Program
A data-management program that makes NHLBI-funded heart, lung, blood, and sleep research data easier to use and share, with strong data security and AI-powered tools.
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Stillbirth Data Hub: Coordinating Center for Big-Data and AI in Stillbirth Research
A national data hub is being built to coordinate data, biorepository, and analytics for stillbirth research using advanced AI and machine learning.
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HEAL Network Coordination Center for HIV, SUD, and criminal-justice research
A national coordinated hub supports studies aiming to improve stability, engagement, and health outcomes for people affected by HIV, substance use disorders, and involvement with the criminal justice system.
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BioData Catalyst Data Management Core program for NHLBI data systems
A data-management core is building and maintaining secure, high-quality data tools to help researchers study heart, lung, blood, and sleep health.
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Coordinating center to improve school meals for young children
A national effort to generate and share practical, evidence-based ways to improve school meals for children 0–11 and help health professionals teach better nutrition.
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Couples-based decision aid to improve HIV prevention choices for women in Uganda
A study tests a couples-focused decision tool to help Ugandan women choose the best HIV prevention option with input from partners.
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CARES: A practical program to help adolescent girls and young women use PrEP in Africa
A program called CARES helps young women in South Africa and Zimbabwe use different PrEP options better, with counseling, reminders, and options for support.
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CARES: a help plan to support PrEP use for adolescent girls and young women in Africa and beyond
A real-world plan to help young women stay on PrEP and reduce HIV risk by using counseling, biomarker feedback, and flexible support options.
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CBT-based mobile program to prevent youth violence
A mobile CBT-based program called Rewire is being tested to help youths and young adults reduce violence-related behaviors in North Carolina.
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Coordinating Center to accelerate translating heart, lung, and blood therapies to patients
A national program to help move promising heart, lung, and blood therapies from the lab into real-world patient care more quickly.
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All of Us Engagement and Retention Innovators program
A large NIH program aims to keep diverse participants connected with the All of Us research effort through human-centered digital tools, education, and community engagement.
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Targeted HIV self-test distribution to engage high-risk men in Kenya
A study tests whether giving HIV self-test kits through women who sell sex can help high-risk men in Kenya learn their status and get care.
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Chronic Kidney Disease of Unknown Cause in Agricultural Communities
A wide study to find what causes a serious kidney disease that affects workers in farming areas, by looking at people in high-risk regions.
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Neonatal Research Network Data Coordinating Center (DCC) 2023-2028
A Data Coordinating Center will support a national network of neonatal studies to improve care for newborns across multiple sites.
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NuMoM2b Heart Health: Following moms after pregnancy to prevent heart disease
This project follows tens of thousands of women after pregnancy to understand how pregnancy complications relate to future heart health and to test remote and hybrid visit options so more people can participate from home.
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Nutrition for Precision Health: Coordinating Center for All of Us data and AI-ready analyses
A national effort to harmonize diet data, digital tools, and AI-ready information from All of Us to improve personalized nutrition research.
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Understanding how congenital Zika affects children over time in Brazil
This project follows children with congenital Zika syndrome in Brazil to learn what factors influence their health and development as they grow.
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Advancing PrEP Access for Women in Georgia
A study to help more women in Georgia get PrEP for HIV prevention through better provider training and a woman-focused decision tool.
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OD-CHESS: a smartphone tool to help reduce overdose risk for people who use multiple substances
A smartphone app-based program designed to reduce overdose risks for people who use drugs and often mix substances, with plans to test its effectiveness in urban and rural communities.
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Community-based prevention for ACEs and substance use impact
A community-wide program tests how combining family supports with trauma-informed help can reduce substance use and related childhood adversity in communities that are hardest hit.
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Safe Bars training to prevent sexual violence in bars and nightclubs
A funded program will test whether Safe Bars bystander training for venue staff reduces sexual violence in alcohol-serving venues.
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Preteen Suicide Risk: Data Coordinating Center
A national project creates a central data hub to support six youth suicide research studies, so clinicians and families can better understand risk and protective factors for children aged 8–12.
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Down Syndrome Clinical Cohort Coordinating Center for INCLUDE (DS-4C)
A nationwide effort to coordinate and harmonize data and biospecimens on people with Down syndrome to help researchers understand and improve DS health across life.
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Down Syndrome Clinical Cohort Coordinating Center for INCLUDE
A nationwide effort to coordinate and harmonize data and biospecimens for people with Down syndrome to help researchers understand DS health across the lifespan.
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DS-4C: Coordinating Center to unify Down syndrome health research
A national effort to coordinate a large, long-term study of people with Down syndrome to collect health data and biospecimens that researchers can use to understand and improve DS health across all ages.
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Down Syndrome Clinical Cohort Coordinating Center for INCLUDE Project
A national coordinating center will unite and harmonize data and biospecimens from DS cohorts to advance health research for individuals with Down syndrome.
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Down syndrome health study hub coordinating center
A national program to improve health for people with Down syndrome by coordinating data, biospecimens, and outreach across many sites.
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Sickle Cell Data and Resource Hub
Creating shared, secure data tools and databases to help people with sickle cell disease, their doctors, and researchers speed up better treatments.
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Family-based mHealth program to prevent early alcohol use by preteens
A mobile-based program helps parents of preteens prevent early alcohol use by providing practical guidance and strategies.
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Innovative Data Core for Stillbirth Research Center
A data and software core is being built to harmonize and analyze information from multiple sites to uncover why stillbirth happens and to support future prevention.
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Administrative Core for Stillbirth Research Coordinating Center
A coordination core is being funded to organize and manage data, collaborations, and administration to help stillbirth research move forward.
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Stillbirth Data Coordinating Center focusing on AI-powered insights
A national data hub is using advanced AI and machine learning to analyze stillbirth data and help researchers find patterns that could prevent or understand stillbirth.
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Pathways to Treatment: Oregon deflection programs for people who use drugs
A multisite study in Oregon looks at how three different deflection programs connect people with substance use disorders to treatment and services, aiming to keep them out of the criminal-legal system.
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RXFP3-Targeted Drugs to Help with Alcohol Use Disorder
A new drug approach aims to block a brain receptor (RXFP3) to reduce alcohol craving and drinking in people with alcohol use disorder.
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PhenX Toolkit as a biomedical knowledgebase to harmonize data
A large NIH project is building a freely accessible collection of standard measurement protocols to help researchers collect consistent data across studies and improve patient care.
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National hub coordinating Down syndrome health cohorts
This project brings together clinical sites and researchers to collect health information and biological samples from people with Down syndrome across their lives so care can improve.
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