NIH-funded research R01 grant

Couples-based decision aid to improve HIV prevention choices for women in Uganda

Official title: Improving Choice and Use of Biomedical HIV Prevention for Women in Uganda: A Couples-Based Approach

Funded at Research Triangle Institute · NIH-11593444 · Data updated 2026-11-12

A study tests a couples-focused decision tool to help Ugandan women choose the best HIV prevention option with input from partners.

More HIV Prevention research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionResearch Triangle Institute
NIH-funded
Lab location1 site (Research Triangle Park, United States)
Project startSeptember 17, 2024
Project endJune 30, 2028
Funding year2026
Award (this year)$338,879
NIH project number3R01MH137873-03S1
Project IDNIH-11593444 on NIH RePORTER

Who could benefit from this research

Could help

Women in Uganda who are considering PrEP options and who may involve a male partner in decision-making, in community or clinic settings.

Less likely to help

Women who prefer stand-alone or individual decision-making without partner involvement may not benefit as much.

What this research studies

This project will implement a paper-based shared decision-making tool called CUPID with health teams in community and clinic settings to help couples discuss and choose among PrEP options. It focuses on real-world settings in Uganda to see how well the tool works and how it can be integrated into routine care. The study emphasizes women's agency while recognizing the role of male partners in prevention decisions, aiming to improve adherence and satisfaction with the chosen PrEP method. Results will inform how to implement couple-based decision support to increase sustainable use of HIV prevention products.

Why it matters

Potential benefit: If successful, the intervention could help more women choose and consistently use the most suitable HIV prevention option with partner support.

How similar studies have gone: Previous work shows that shared decision-making can influence treatment choices and adherence in some health areas, but this is a novel application to HIV prevention in this setting.

Where this research is happening

  • Research Triangle Institute
    Research Triangle Park, United States
    Active

Researchers

  • Principal investigator: Minnis, Alexandra M — Research Triangle Institute
  • Study coordinator: Minnis, Alexandra M

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.