Community-based prevention for ACEs and substance use impact
Official title: RFA-CE-22-009 Rigorous Evaluation of Community-Level Substance Use and Overdose Prevention Frameworks that Incorporate ACEs-Related Prevention Strategies
Funded at Research Triangle Institute · NIH-11422066 · Data updated 2026-11-12
A community-wide program tests how combining family supports with trauma-informed help can reduce substance use and related childhood adversity in communities that are hardest hit.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Research Triangle Institute NIH-funded |
| Lab location | 1 site (Research Triangle Park, United States) |
| Project start | September 30, 2022 |
| Project end | September 29, 2027 |
| Funding year | 2026 |
| Award (this year) | $831,160 |
| NIH project number | 5U01CE003482-05 |
| Project ID | NIH-11422066 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal participants are families in New Jersey communities with elevated ACEs and substance-use risk who can engage with family supports and trauma-informed services.
✕Less likely to help
Families not connected to available community resources or unwilling to participate in coordinated supports may see limited benefit.
What this research studies
This project tests a community-level approach to prevent substance use by supporting families and linking them to resources through trained Family Advocates. It combines the evidence-based Strengthening Families Program with trauma-informed family support to expand access and coordination of care in 20 New Jersey communities. Using a Hybrid Type 1 design, researchers will measure how well the integrated approach works in real-world settings while also studying how it is implemented in the field. The goal is to determine whether this combined strategy can lower ACEs and substance use disparities in high-need areas.
Why it matters
Potential benefit: If successful, communities could see fewer ACEs and lower substance use among youth and families through better access to coordinated supports.
How similar studies have gone: Previous work supports individual components (ACE prevention, family programs); this study tests their integrated use in real communities, which is relatively novel.
Where this research is happening
-
Research Triangle Institute
Research Triangle Park, United States Active
Researchers
- Principal investigator: Graham, Phillip W — Research Triangle Institute
- Study coordinator: Graham, Phillip W
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.