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Clinical trials and research at Regeneron Pharmaceuticals
As of November 12, 2026, Find a Trial lists 70 clinical trials run by Regeneron Pharmaceuticals that are recruiting, at sites in 42 countries (most in United States (57), Spain (20), United Kingdom (19)). By phase: Phase 3 (24), Phase 1/2 (16), Phase 2 (13), Phase 1 (12). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 70Clinical trials
- 42Countries
Newest trials
All recruiting trials (70)
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ALN-CIDEB in adults with MASLD to see if it helps the liver
This study tests whether ALN-CIDEB can help adults with MASLD and its liver damage compared to placebo.
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Olatorepatide vs placebo for adults with moderate-to-severe hidradenitis suppurativa who are overweight
This study tests whether olatorepatide can help people with hidradenitis suppurativa who are overweight or obese.
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Three antibodies plus heparin in adults with end-stage kidney disease on dialysis
This study tests three investigational antibodies (REGN9933, REGN7508, REGN9533) in adults with end-stage kidney disease on hemodialysis who are already using heparin to prevent clots.
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REGN17235 for CCUS and LR-MDS with SF3B1 mutation
This study tests REGN17235 in adults with CCUS or LR-MDS carrying an SF3B1 mutation to see if it is safe and tolerable and to get early signals of efficacy.
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Blood-clot prevention with REGN7508 and REGN9933 in people with PICC lines
This study tests whether REGN7508 and REGN9933 can help prevent blood clots in people who have a PICC line.
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Olatorepatide in adults who are overweight or have obesity (without diabetes) test of safety and dosing
This study tests olatorepatide versus placebo to see if it can safely help adults who are overweight or obese lose weight at different doses.
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REGN22530 for Adults With Primary Open Angle Glaucoma or Ocular Hypertension
This study tests REGN22530 in adults with POAG or ocular hypertension to see if it can lower eye pressure and what kind of side effects it may have.
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Cat-allergy eye allergy treatment with REGN-2Cat and study drugs in adults and kids
This trial tests fel d 1 monoclonal antibodies (freneslerbart and mevonlerbart) alone or together to see if they reduce cat‑induced allergic conjunctivitis symptoms compared with placebo in adults and children.
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ALN-CIDEB for adults with fibrotic MASH (phase 2)
This phase 2 study tests ALN-CIDEB versus placebo to see if it can reduce liver fat, injury, and scarring in adults with fibrotic MASH.
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Preventing stroke and systemic embolism in adults with atrial fibrillation using REGN7508 compared with apixaban
This trial tests REGN7508 in adults with atrial fibrillation to see if it can prevent stroke and blood clots better or as well as apixaban.
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Linvoseltamab with pre-dose Tocilizumab to reduce CRS in adults with relapsed/refractory multiple myeloma
This study tests whether giving tocilizumab before the first dose of linvoseltamab can lower the risk of cytokine release syndrome in adults with relapsed/refractory multiple myeloma who have had at least four prior therapies.
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REGN15505 Alone or With Cemiplimab or REGN4336 in Advanced Prostate Cancer and Kidney Cancer
This trial tests REGN15505 by itself or with cemiplimab or REGN4336 to see if it helps adults with metastatic castration-resistant prostate cancer or clear cell renal cell carcinoma.
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Safety and drug levels of REGN20934 in adults with overweight or obesity
This study tests REGN20934 to see if it is safe and how it behaves in the body in adults who are overweight or have obesity.
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Dupilumab added to standard COPD care after a flare-up
This study tests whether adding dupilumab to usual COPD care after a severe flare requiring hospitalization can reduce the chance of another flare.
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BPX-601 CAR T-Cell Therapy for Relapsed, Metastatic Prostate Cancer
This study tests BPX-601, a patient-derived CAR T-cell therapy, to see if it can help adults with relapsed, metastatic, castration-resistant prostate cancer.
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First-in-human test of REGN20423 in healthy adults and adults with eczema
This study tests REGN20423 in healthy adults and adults with atopic dermatitis to see how it behaves in the body and whether it helps eczema symptoms.
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ALN-PNP with or without a GLP-1/GIP receptor agonist in adults with PNPLA3-related MASLD
This study tests ALN-PNP, with or without tirzepatide, to see if it can reduce liver fat in adults with PNPLA3-related MASLD.
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First-in-human test of REGN22044 safety and how it behaves in the body
This first-in-human study will test REGN22044 in healthy adults to see if it is safe, tolerable, and how much stays in the blood after a single dose (with a placebo comparison).
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Treatment and prevention of blood clots in adults with cancer
This study tests REGN7508 against apixaban to see if it can treat and prevent blood clots in adults with or without cancer, including those with cancer-related clots in the legs and lungs.
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REGN17372 plus linvoseltamab tolerability for adults with relapsed/refractory multiple myeloma
This trial tests whether giving REGN17372 together with linvoseltamab is safe and what dose works for adults whose multiple myeloma has come back or stopped responding.
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Preventing stroke and systemic embolism in adults with atrial fibrillation who can't use oral blood thinners
This trial tests two experimental drugs, REGN7508 and REGN9933, to see if they reduce ischemic stroke or systemic embolism in adults with atrial fibrillation who cannot or choose not to take oral blood thinners.
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REGN7508 to prevent blood clots in adults with solid tumors
This study will test whether the experimental drug REGN7508 can prevent cancer-associated blood clots in adults with solid tumors who are receiving or about to start anticancer treatment or recovering from surgery.
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Linvoseltamab vs. Daratumumab in high-risk smoldering myeloma
This study tests whether linvoseltamab can delay progression to active myeloma better than daratumumab in people with high-risk smoldering multiple myeloma.
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Reducing blood clots after leg artery procedures with Factor XI inhibitors in adults with PAD
This trial tests two drugs, REGN7508 and REGN9933, to see if they lower the chance of dangerous blood clots after leg artery restoration procedures in adults with peripheral artery disease.
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REGN13335 for adults with pulmonary arterial hypertension (PAH)
Researchers will test whether the experimental antibody REGN13335 is safe and helps adults with pulmonary arterial hypertension who are already taking other PAH medicines.
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ANGPTL3 inhibition for adults with diabetic kidney disease
This study tests whether two drugs that block ANGPTL3, ALN-ANG3 and evinacumab, are safe and help adults with type 2 diabetes who have diabetic kidney disease.
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Mibavademab for adult women with functional hypothalamic amenorrhea
This trial tests whether the experimental drug mibavademab helps adult women with functional hypothalamic amenorrhea make the hormones needed to resume ovulation and menstrual cycles.
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Eye injection of pozelimab for geographic atrophy in adults
This study will test whether injections of pozelimab into the eye are safe and well tolerated in adults with geographic atrophy from age-related macular degeneration.
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Linvoseltamab alone or with carfilzomib versus standard combination regimens for adults with relapsed/refractory multiple myeloma.
This trial tests whether linvoseltamab alone or together with carfilzomib works better than standard combination treatments for adults with relapsed or refractory multiple myeloma who have had 1–3 prior therapies.
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Mibavademab for adults and children with generalized lipodystrophy
This trial will test whether mibavademab helps adults and children with generalized lipodystrophy by improving blood sugar, lowering triglycerides, and reducing liver fat while checking safety and drug levels.
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Mibavademab for obesity caused by leptin (LEP) gene mutations in children, adolescents, and adults
This trial will try mibavademab in children, adolescents, and adults with leptin gene–related obesity to help control body weight and check safety.
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ALN-SNCA in adults with early Parkinson's disease
This trial will test ALN-SNCA in adults with early Parkinson's disease to see if it is safe, well tolerated, and lowers α-synuclein in cerebrospinal fluid.
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REGN7508 versus aspirin to prevent blood clots after single-knee replacement
This tests whether REGN7508 or aspirin better prevents blood clots in adults having elective single-knee replacement surgery.
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ALN-CFB for adults with PNH who remain anemic on C5 inhibitors
This trial will test ALN-CFB, an experimental siRNA medicine, versus placebo in adults with PNH who remain anemic despite taking a C5 inhibitor.
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Safety of two new clot-preventing medicines for adults with atrial fibrillation on anticoagulation
This trial will test two experimental medicines, REGN7508 and REGN9933, against apixaban to see if they prevent clots with acceptable bleeding risk in adults with atrial fibrillation who need long-term anticoagulation.
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Pozelimab + cemdisiran for adults with PNH whose current treatment isn't working
This trial tests whether combining pozelimab and cemdisiran can better reduce hemolysis in adults with PNH whose C5 inhibitor treatment isn’t controlling their disease.
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Ubamatamab with or without REGN7075 for adults with advanced or metastatic non-small cell lung cancer
This trial will try ubamatamab alone and with REGN7075 in adults with advanced or metastatic non-small cell lung cancer to see if they control the cancer and will try sarilumab to manage immune-related side effects.
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Pozelimab safety in children 1 to 5 with CHAPLE disease
This trial will test whether pozelimab is safe and tolerable in children ages 1 to 5 who have CHAPLE disease.
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Dupilumab for young children with eosinophilic esophagitis (food-pipe inflammation)
This study will test whether 24 weeks of dupilumab helps infants and toddlers with active eosinophilic esophagitis improve feeding and reduce esophageal inflammation.
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REGN7508 versus apixaban and enoxaparin for preventing blood clots after total knee replacement
This trial will test whether REGN7508 prevents blood clots after elective one-sided total knee replacement in adults compared with apixaban, enoxaparin, or placebo.
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Increasing doses of bispecific antibodies for adults with lupus nephritis
This research will try different doses of bispecific antibody medicines in adults with lupus nephritis to see if they are safe and tolerable over long-term follow-up.
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Long-term safety and effectiveness follow-up after gene-modified T cell treatment in adults
This follows adults who received gene-modified T cell therapy to see whether the treatment stays safe and continues to work over the long term.
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Ubamatamab alone and with other cancer drugs for platinum-resistant ovarian, fallopian tube, or primary peritoneal cancer
This trial will test whether ubamatamab by itself or combined with bevacizumab, cemiplimab, fianlimab, or pegylated liposomal doxorubicin helps adults with platinum-resistant ovarian, fallopian tube, or primary peritoneal cancer.
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Adding fianlimab to cemiplimab versus cemiplimab alone for recurrent or metastatic head and neck squamous cell carcinoma
This test sees if adding the experimental drug fianlimab to cemiplimab works better than cemiplimab alone for people with recurrent or metastatic PD-L1–positive head and neck squamous cell carcinoma.
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Testing REGN7945 with linvoseltamab for relapsed multiple myeloma
This study is testing a new drug called REGN7945 combined with linvoseltamab to see if it helps adults with relapsed multiple myeloma better than linvoseltamab alone.
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Using cemiplimab to treat early-stage skin cancer
This study tests if injecting a new immune treatment called cemiplimab directly into early-stage skin cancer can work better than regular surgery.
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Investigating a new treatment for geographic atrophy in age-related macular degeneration
This study is testing a new treatment using two drugs to see if they can slow down the worsening of geographic atrophy in adults with age-related macular degeneration.
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Immune cell therapy for recurrent ovarian cancer
This study is testing a new immune cell therapy called 27T51 to see if it can help women with recurrent ovarian cancer feel better and fight their disease.
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Testing a new drug for advanced solid tumors
This study is testing a new drug called REGN10597 to see if it is safe and effective for adults with advanced solid tumors like melanoma and kidney cancer.
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Gene therapy for treating hemophilia B
This study is testing a new gene therapy to see if it can help people with severe or moderately severe hemophilia B produce their own clotting factor IX and how safe it is for both adults and kids.
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Testing a new drug for ALS caused by SOD1 gene mutations
This study is testing a new drug for adults with ALS caused by SOD1 gene mutations to see if it's safe and how it affects their symptoms and certain markers in their blood and spinal fluid.
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Testing linvoseltamab for treating relapsed or refractory AL amyloidosis in adults
This study is testing a new drug called linvoseltamab to see if it can help adults with relapsed or refractory AL amyloidosis feel better and improve their organ function.
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Combining two experimental drugs for advanced melanoma treatment
This study is testing if a new combination of two experimental drugs can help people with advanced melanoma more than the current approved treatments.
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Testing a new drug combination for relapsed or refractory follicular and marginal zone lymphoma
This study is testing a new combination of drugs to see if it can help adults with relapsed or hard-to-treat follicular or marginal zone lymphoma feel better compared to standard treatment.
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Testing linvoseltamab for eliminating abnormal plasma cells in patients with high-risk MGUS or smoldering multiple myeloma
This study is testing if a new drug called linvoseltamab can help get rid of abnormal plasma cells in patients with high-risk MGUS or smoldering multiple myeloma.
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Odronextamab with chemo vs rituximab with chemo in untreated DLBCL
A new treatment approach using odronextamab plus chemotherapy is being tested to see if it works better and is as safe as rituximab plus chemotherapy for adults with newly diagnosed diffuse large B-cell lymphoma.
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Testing a new drug called odronextamab for treating follicular lymphoma
This study is testing a new drug called odronextamab to see if it can safely and effectively treat people with follicular lymphoma who haven't received treatment before.
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Gene therapy for children with hearing loss from otoferlin mutations
This study is testing a new gene therapy called DB-OTO to see if it can help children with hearing loss caused by specific genetic mutations improve their hearing.
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Long-term treatment for patients with paroxysmal nocturnal hemoglobinuria using pozelimab and cemdisiran
This study is testing a new combination of two experimental drugs, pozelimab and cemdisiran, to see if they can safely help adults with paroxysmal nocturnal hemoglobinuria over a long period of time.
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Comparing linvoseltamab to a combination of three other cancer drugs for relapsed/refractory multiple myeloma
This study is testing if a new drug called linvoseltamab works better than a standard combination of three other cancer drugs for adults with relapsed or refractory multiple myeloma.
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Testing a new drug combination for aggressive B-cell lymphoma
This study is testing a new combination of two experimental drugs to see if they can help adults with aggressive B-cell lymphoma that hasn’t responded to other treatments.
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ALN-PNP safety and tolerability in healthy adults and adults with MASLD
This first-in-human trial tests whether the experimental drug ALN-PNP is safe and well tolerated in healthy adults and in adults with MASLD who carry a specific PNPLA3 gene variant.
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Gene silencing treatment for chronic liver disease in genetically at-risk adults
This study is testing a new drug to see if it can help adults at higher genetic risk for liver disease by reducing liver damage and inflammation.
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Examining the effects of linvoseltamab with other cancer treatments for multiple myeloma
This study is testing a new drug called linvoseltamab along with other cancer treatments to see how well it works and how safe it is for adults with relapsed or refractory multiple myeloma.
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Investigating the safety and effectiveness of REGN4336 for advanced prostate cancer
This study is testing a new drug called REGN4336, alone and with other treatments, to see if it can safely help adults with advanced prostate cancer shrink their tumors.
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Observing kidney transplant outcomes in patients treated with vonsetamig
This study looks at how well kidney transplants work in adults who were treated with vonsetamig before their transplant to see how it affects their health afterward.
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Investigating the safety and effectiveness of REGN5668 with other drugs for advanced ovarian and uterine cancers
This study is testing if a new drug called REGN5668, used with other medications, can safely help people with advanced ovarian or uterine cancers.
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Evaluating the safety and effectiveness of REGN5678 alone or with cemiplimab for advanced prostate and kidney cancer
This study is testing if a new drug called REGN5678, alone or with another drug called cemiplimab, can safely shrink tumors in adults with advanced prostate and kidney cancer.
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Testing REGN5458 for patients with relapsed or refractory multiple myeloma
This study is testing a new drug called REGN5458 to see if it can safely help adults with relapsed or refractory multiple myeloma who have few treatment options.
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Treatment for recurrent ovarian and other MUC16+ cancers using REGN4018 and cemiplimab
This study is testing if a new treatment combining REGN4018 and cemiplimab can help adults with recurrent ovarian and other MUC16+ cancers feel better when other options have run out.
Quick answers
How many clinical trials run by Regeneron Pharmaceuticals are recruiting right now?
70, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 42 countries. The most sites are in United States (57 trials), Spain (20 trials), United Kingdom (19 trials), South Korea (19 trials), France (16 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 3: 24, Phase 1/2: 16, Phase 2: 13, Phase 1: 12. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.