Sponsor or institution
Clinical trials and research at Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
As of November 12, 2026, Find a Trial lists 3 clinical trials run by Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center that are recruiting, in United States. By phase: Phase 2 (2), Phase 2/3 (1). There are also 69 NIH-funded research projects at this institution, with $36.8 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 69NIH research projects
- 1Country
Newest trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Low-dose ketamine for sickle cell vaso-occlusive pain in children and young adults | Phase 2 | Torrance, California | Recruiting | Jan 27, 2026 |
| Cannabidiol (Epidiolex) for neurobehavioral symptoms in Sanfilippo syndrome | Phase 2/3 | Torrance, California | Recruiting | Mar 27, 2024 |
| Psilocybin therapy for demoralization in palliative care patients | Phase 2 | Greenbrae, California and 4 other locations | Recruiting | Jun 3, 2022 |
All recruiting trials (3)
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Low-dose ketamine for sickle cell vaso-occlusive pain in children and young adults
This trial will test whether adding a low (sub-dissociative) dose ketamine infusion to usual IV opioid pain medicine helps children and young adults (ages 5–20) with sickle cell disease have better pain relief and remain safe during a vaso-occlusive episode.
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Cannabidiol (Epidiolex) for neurobehavioral symptoms in Sanfilippo syndrome
This trial will test whether Epidiolex (a pharmaceutical cannabidiol) is safe and can help children and young people with Sanfilippo syndrome reduce neurobehavioral problems and improve daily functioning.
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Psilocybin therapy for demoralization in palliative care patients
This study is testing if psilocybin therapy can help improve feelings of hopelessness in adults with serious illnesses who have a life expectancy of two years or less, compared to ketamine.
NIH-funded research (newest 40 of 69)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Immunometabolic and epigenetic changes in the mouth’s immunity in diabetes-related thrush
This grant looks at why people with diabetes get a higher risk of oral thrush and how high blood sugar affects the mouth’s defenses against Candida albicans.
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Non-invasive heart fat markers to predict ASCVD risk
Aging adults who don’t yet have heart disease may get a clearer picture of their risk by using CT scans to study fat around the heart and arteries.
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Asthma and IgE: How nerve signals in the lungs may boost allergy antibodies
A short, patient-friendly study will explore how a nerve-released substance called substance P may push immune cells to make more allergy-causing IgE in asthma.
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Time-limited trials to guide care for seriously ill patients in the ICU
A real-world study tests using structured, time-limited conversations and agreed-upon treatment plans to help seriously ill patients and their families avoid non-beneficial ICU care.
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Cellular aging and lung disease in Down syndrome babies and adults
A study will explore how aging cells may drive lung problems in people with Down syndrome from birth through adulthood.
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New CPET approach to tell apart heart problems from muscle weakness
A doctor-guided study tests a modified cardiopulmonary exercise test that adds simple muscle-power measurements to better tell whether shortness of breath comes from heart disease or from weak, fatigued muscles.
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Sleep and Hormone Clocks Behind Insulin Resistance in Adults
Researchers will study how missing sleep and shifting sleep times affect insulin resistance in adults, aiming to understand why night workers are at higher risk for type 2 diabetes.
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Pulmonary nerve signals shaping antibody production against pneumonia
A study to understand how the lungs’ sensory nerves influence the body’s antibody response to pneumonia-causing bacteria.
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Regulation of Candida biofilms on central venous catheters through transcriptional networks
A study to understand how Candida albicans forms biofilms on central venous catheters using real-life models to identify key transcription factors.
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Mouse model of neonatal Candida colonization and mucosal immunity
Researchers are studying how Candida albicans living in newborns’ mouths shapes early immune responses and mucosal health using a new baby-mouse model.
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Oral fungal commensals and the body's tissue-building immunity
Researchers are studying how the common oral fungus Candida albicans helps shape the immune system and tissue responses to keep the mouth healthy, especially in people with AIDS-related conditions.
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Immune-boosting strategies to help fight invasive mucormycosis in cancer patients
A research project tests immune-boosting approaches that could help cancer patients with a serious fungal infection improve their response to antifungal therapy.
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Understanding how the body fights Mucormycosis by targeting fungal metabolism
A research project is exploring how immune cells and fat-related molecules work together to stop a dangerous fungal infection called Mucormycosis, with the goal of finding new ways to help patients.
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Mucormycosis: new targets to stop deadly fungal invasion
A patient-facing overview of a funding opportunity aiming to understand and block how Mucorales fungi invade the body in people with weakened immune systems.
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Genomics and Transcriptional Core supports MUCOR mycosis research across teams
A genomics and transcriptomics core is joining a large project to study how the immune system and the fungus mucor interact, aiming to improve diagnosis and treatment of mucormycosis.
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MUCOR-ADVANCE: Better Diagnosis and Care for Mucormycosis in High-Risk Patients
A multi-center project aims to improve how mucormycosis is diagnosed and managed in people with weakened immune systems by collecting patient samples and clinical data to guide risk-based care.
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Administrative Core supporting a mycology and infectious disease research program
A central Administrative Core helps coordinate a multidisciplinary program focused on basic mycology and infectious diseases, aiming to advance discoveries and collaboration across multiple projects.
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MUCORmycosis: unlocking better diagnosis and care for at-risk patients
A multi-institution program aims to understand how MUCORmycosis develops in people with risk factors like diabetes, steroids, or weakened immunity, and use that knowledge to improve diagnosis and treatment.
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Improving pregnancy high-blood-pressure care in community clinics
A plan to help doctors in community clinics follow guidelines to prevent preeclampsia with low-dose aspirin for pregnant people at risk.
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Understanding why some blood infections with Candida and MRSA are persistent
Researchers are studying why certain fungal and bacterial infections stay stubborn in hospitalized patients and how the body’s immune system responds over time.
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Epigenetic and immune- signaling clues in candida bloodstream infections
This grant looks at why Candida infections in the blood can be deadly and how patient genes and immune responses might explain who struggles or survives.
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Epigenomic clues and immune context in stubborn MRSA bloodstream infections
Researchers are studying why some MRSA bloodstream infections persist despite antibiotics and how the immune system and bacterial DNA packaging (epigenetics) influence this, with the goal of better treatments.
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Computational Modeling Core for multi-omics and infection research
A core center uses advanced computer methods to analyze and predict how infections like Candida albicans behave, by combining data from different biological layers and studies.
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Bioinformatics and Data Management Core for High‑throughput Genomics Projects
A core facility will manage and analyze large genomic data, helping multiple projects at Harbor-UCLA to store, process, and share results.
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Immunomics and Epigenomics Core for MRSA and Candida Blood Infections
A center-funded project will study how the immune system and epigenetic changes relate to MRSA and Candida bloodstream infections and how these factors affect antibiotic response.
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Administrative Core for a Center on Systems Epigenomics of Persistent Bloodstream Infection
A center project is building a coordinated, data-driven program to study why some bloodstream infections persist despite therapy, with a focus on host-pathogen interactions and epigenomics.
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Systems Epigenomics of Persistent Bloodstream Infection
A national research effort to understand why some bloodstream infections stay in the body despite appropriate antibiotic treatment, with the goal of improving care for people with dangerous infections.
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Tryptophan metabolism and fibroid disease: a new path to understanding and treatment
Researchers are studying how tryptophan breakdown enzymes (TDO2 and IDO1) behave in fibroids, with a focus on African American patients, to find new ways to treat fibroid growth.
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Advanced confocal microscope for clearer cell and cancer imaging
This project brings a new high-resolution microscope to researchers who study cancer, development, and cell biology so they can see cells and tissues more clearly and safely.
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Deciphering how BRCA1 and ATR work together to prevent genome instability in breast cancer
A research project aims to understand how BRCA1, ATR, and METTL3 interact to keep DNA damage from causing cancer progression, with a focus on breast cancer cells.
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How human insulin-producing islets form and can be made stronger
This project aims to grow more uniform, scalable insulin-producing cell clusters from human stem cells and help them avoid immune attack for adults with brittle type 1 diabetes.
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How immune signals IL-33 and SPRR affect mouth yeast infections
Researchers are testing whether two immune signals, IL‑33 and SPRR, can help the mouth heal from Candida (yeast) infections in people with weakened immune systems like those with HIV or cancer.
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Perinatal nicotine exposure and asthma risk: how lung immune cells react
This grant looks at how nicotine exposure before birth may change the lungs’ immune cells and raise the risk of allergic asthma in offspring.
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Cyclic Antifungal Peptides for Drug-Resistant Invasive Fungal Infections
Researchers are testing new cyclic antifungal peptides to help treating drug-resistant fungal infections in people with weakened immune systems.
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How Ataxia Telangiectasia harms the cerebellum
Researchers are looking at whether losing two DNA-repair proteins causes the cerebellum damage that leads to ataxia in children and young adults with Ataxia Telangiectasia.
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Early lung cell aging in Down syndrome
This project will find out how aged lung cells and immune signals contribute to breathing and lung problems in people with Down syndrome, especially infants and children.
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Understanding how a dangerous fungus causes severe infections
This project aims to discover how a common fungus, Aspergillus fumigatus, causes life-threatening infections, especially in people with weakened immune systems.
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Plant-Focused Eating for Diabetes and Kidney Disease
This research explores if a plant-focused eating plan can help people with both diabetes and chronic kidney disease manage their health.
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Understanding Suicidal Behavior in Homeless Teens During the COVID-19 Pandemic
This project aims to understand how the COVID-19 pandemic affected suicidal thoughts and actions in young people experiencing homelessness.
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How immune signals shape lung growth in Down syndrome
This project looks at whether type I interferon immune signals change lung development before birth in babies with Down syndrome.
Quick answers
How many clinical trials run by Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center are recruiting right now?
3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
All of them have sites in United States. Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 2, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.