Plant-Focused Eating for Diabetes and Kidney Disease
Official title: Plant-Focused Nutrition in Patients with Diabetes and Chronic Kidney Disease (PLAFOND Study): A Pilot/Feasibility Study
Funded at Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center · NIH-11160524 · Data updated 2026-11-12
This research explores if a plant-focused eating plan can help people with both diabetes and chronic kidney disease manage their health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center NIH-funded |
| Lab location | 1 site (Torrance, United States) |
| Project start | July 10, 2023 |
| Project end | May 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $277,389 |
| NIH project number | 5R01DK132875-03 |
| Project ID | NIH-11160524 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are adults aged 21 and older who have both diabetes and chronic kidney disease.
✕Less likely to help
Patients without both diabetes and chronic kidney disease may not directly benefit from this specific dietary intervention.
What this research studies
Many people with diabetes also have chronic kidney disease, and it's not always clear what the best diet is for them. While some diets recommend low-carbohydrate and low-fat for diabetes, others suggest low-protein, plant-based meals for kidney disease. This project aims to understand if a plant-focused diet can safely and effectively support kidney health without negatively impacting diabetes management. We want to see if this approach can slow down kidney disease progression and improve overall well-being.
Why it matters
Potential benefit: If successful, this research could provide clearer dietary guidance for patients with both diabetes and chronic kidney disease, potentially slowing disease progression.
How similar studies have gone: There is ongoing debate and conflicting guidelines regarding dietary protein intake in CKD/DM, making this a novel exploration of plant-based diets in this specific patient group.
Where this research is happening
-
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Torrance, United States Active
Researchers
- Principal investigator: Kalantar-Zadeh, Kamyar — Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
- Study coordinator: Kalantar-Zadeh, Kamyar
Related research
Other NIH-funded projects on the same topics.
-
Unrecognized Primary Aldosteronism and Kidney Disease in Diabetes
A study at Brigham and Women’s Hospital will explore whether unrecognized primary aldosteronism contributes to kidney disease and heart risk in people with diabetes.
-
Rapid, multi-drug initiation for people with CKD and type 2 diabetes
A small study will try starting several key diabetes and kidney medicines at the same time in adults with CKD and type 2 diabetes to see if this fast plan is safe and helpful.
-
Improving heart- and kidney-protective treatment for people with type 2 diabetes and chronic kidney disease
This project will help people with type 2 diabetes and chronic kidney disease get proven medicines that protect the heart and kidneys but are often missed.
-
Stronger bones for people with both diabetes and chronic kidney disease
This work tests whether combining treatments that build bone mass and improve bone quality can make bones stronger for people who have both diabetes and chronic kidney disease.
-
Investigating how unrecognized primary aldosteronism contributes to kidney disease in diabetes
This study is looking at how a condition called primary aldosteronism might affect kidney health in people with diabetes, and it aims to find those who may not know they have it so they can get the right care to protect their kidneys.
-
Improving bone health in patients with diabetes and chronic kidney disease
This study is looking at how diabetes and chronic kidney disease can affect your bones and increase the risk of fractures, and it aims to find better treatments to help strengthen bones for people dealing with both conditions.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.