Sponsor or institution
Clinical trials and research at Louis Stokes Cleveland VA Medical Center
As of November 12, 2026, Find a Trial lists 67 NIH-funded research projects at this institution. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 67NIH research projects
NIH-funded research (newest 40 of 67)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Smart, self-placing electric bandage to heal ischemic wounds
A new untethered, smart bandage uses electrical stimulation and real-time wound monitoring to help heal chronic ischemic wounds in veterans.
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Personalized modular pressure-relief cushions to prevent bedsores for wheelchair users
A personalized, adjustable cushion system uses a fitting algorithm to tailor pressure relief for wheelchair users and help prevent pressure injuries.
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Smart personalized electric bandage for faster healing of ischemic wounds
A wearable electric bandage that delivers personalized electrical pulses and monitors wounds to help people with chronic ischemic wounds heal faster.
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Center for Functional Electrical Stimulation (FES)
A program that studies how external electrical stimulation can help people with nerve or brain injuries regain function and improve rehabilitation.
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Personalized prediction of pressure sores after spinal cord injury
This project will use body measures, muscle fat levels, and genetic information to predict which people with spinal cord injury are most likely to develop pressure sores so prevention can be personalized.
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Targeting a sugar pathway to help treat AML
Aims to explore whether dialing down a specific sugar-adding pathway can slow or stop acute myeloid leukemia in patients.
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How spinal cord stimulation changes brain connections in chronic pain
Using harmless brain recordings (near-infrared light and EEG), researchers will look at how spinal cord stimulation affects brain connections in people with chronic neuropathic back pain.
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Synthetic platelet-inspired therapy to protect brain implants and improve recording stability
A patient-facing summary of a project testing a platelet-inspired nanoparticle system that delivers anti-inflammatory drugs at brain implant sites to keep microelectrode recordings clearer longer.
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Implanted biomimetic device to prevent pressure injuries in people with spinal cord injury
A implanted, battery-powered device would provide automatic weight shifting to help prevent pressure injuries in people with spinal cord injury who have limited mobility.
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Gentle electrical rectal stimulation to help bowel emptying after spinal cord injury
This project uses gentle electrical stimulation of the rectum to help people with spinal cord injury empty their bowels more easily.
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Deep brain stimulation to improve visual search in Parkinson’s disease
A brain stimulation approach is explored to help people with Parkinson’s find things more easily in their surroundings by improving how they visually search and scan the environment.
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Advanced Platform Technology Center for Veterans’ Assistive and Restorative Devices
A center based at a VA medical center helps develop and test new devices and therapies to improve the everyday lives of disabled Veterans.
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Creating personalized seating cushions to prevent pressure injuries for wheelchair users
This study is all about creating special cushions that help keep elderly Veterans and people with spinal cord injuries comfortable and safe in their wheelchairs by reducing pressure on their bodies, using smart materials and personalized designs based on what users need.
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FES+BMI Neuroprosthesis for Home Use in Chronic Tetraplegia
A home-use brain-controlled hand prosthesis that helps people with chronic spinal cord injury regain everyday hand movements.
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Restoring sensation in amputated limbs for veterans with diabetic neuropathy
This study is looking to help veterans who have lost lower limbs due to diabetic peripheral neuropathy by using special electrodes to create sensations that feel like they're coming from their missing foot, which could improve their daily activities and overall limb health.
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Nerve stimulation and wearable sensors to improve walking after partial spinal cord injury
Using wearable sensors and targeted nerve stimulation to help Veterans with incomplete spinal cord injury walk faster and more steadily so they can participate in community activities.
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Brain implants that both record signals and deliver medicine
This project creates tiny brain implants that read neural activity and release drugs locally to help people who need long-term brain–computer interfaces, especially Veterans with severe motor loss.
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NK cells and hepatitis C–related liver cancer
This project looks at whether immune cells called natural killer (NK) cells help control liver cancer that can follow hepatitis C, especially in older patients.
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How the CHCHD2 gene affects Parkinson’s and other Lewy body diseases
Researchers are exploring whether restoring a mitochondrial gene called CHCHD2 can reduce harmful protein clumps and cell damage in people with Parkinson’s disease and related Lewy body conditions.
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Blocking a sugar-processing pathway inside leukemia cells to treat acute myeloid leukemia
This project aims to block a sugar-processing pathway (the hexosamine biosynthetic pathway) and reduce O-GlcNAc on proteins to kill AML cells while sparing normal blood cells in adults with AML.
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Identifying risk factors for pressure injuries in people with spinal cord injuries
This study is looking into why some people with spinal cord injuries get pressure injuries while others don’t, and it aims to find ways to predict who might be at risk so that we can help them stay healthy and improve their quality of life.
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Targeting Factor XII to Slow Ovarian Cancer Spread and Blood Clots
A researcher team will study how blocking Factor XII may slow ovarian cancer spread and reduce dangerous blood clots in patients who have ovarian cancer, with a focus on women veterans.
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Understanding why foot displacements happen in power wheelchairs for Veterans with SCI/D
A study aims to uncover why some Veterans with spinal cord injuries have their feet slip off wheelchair footplates, causing injuries.
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Using targeted nerve stimulation to improve bladder control in patients with neurogenic detrusor overactivity.
This study is exploring a new way to help people with spinal cord injuries or certain nerve-related conditions who struggle with bladder control, by using a special technique that stimulates nerves at the right times to improve bladder function and make life easier, especially for veterans.
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Improving implantable connectors for treating nerve disorders
This study is working on improving tiny connectors that can be safely placed in the body to help people with nerve issues, like trouble walking after a stroke or feeling in amputated limbs, and it aims to gather information that could lead to future treatments for these conditions.
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Understanding genetic and environmental factors affecting vision problems in veterans
This study is looking at how genes and the environment affect common eye problems like glaucoma and diabetic retinopathy in veterans, using information from a large group of over 616,000 veterans to help improve care for these conditions.
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Improving arm and hand movement for people with severe spinal cord injuries
This study is working on new technologies to help people with severe neck injuries regain movement in their arms and hands, making it easier for them to do everyday tasks and improve their quality of life.
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Protecting Brain Implants from Infection
This project is creating a special coating for brain implants to help reduce inflammation and improve their performance.
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How mitochondrial DNA drives inflammation after sudden cardiac arrest
This project looks at whether damaged mitochondrial DNA causes inflammation that harms adults who survive sudden cardiac arrest.
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Understanding STEAP4 in diabetic eye disease
This research explores how a protein called STEAP4 contributes to diabetic retinopathy, a serious eye condition that can lead to vision loss in people with diabetes.
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Investigating new treatments for acute myeloid leukemia using plant-derived compounds
This study is looking at a natural compound from plants that might help fight acute myeloid leukemia (AML) by slowing down the growth of cancer cells, and they're testing it in mice to find the best way to help patients like you.
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AI imaging to personalize rectal cancer care
Using artificial intelligence to read scans and help doctors pick the best treatment for people with rectal cancer, especially Veterans.
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Understanding breathing patterns in people with obstructive sleep apnea
This study is looking at how your breathing patterns can help us understand if you'll stick with your sleep apnea treatment, so we can improve care for people like you who use positive airway pressure therapy.
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Improving the translation of medical research for Veterans' healthcare
This study is all about helping researchers at the VA turn their medical discoveries into real-life treatments and services that can improve the health of Veterans, by providing them with the support and guidance they need to make it happen.
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How TRPC6 channels affect the healing of blood vessels
This study is looking at how certain channels in blood vessel cells can affect their ability to heal after injuries, especially in older adults and veterans, with the goal of finding new ways to help these cells recover better and prevent problems after procedures.
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Investigating how reducing Glut1 can prevent diabetes-related complications
This study is looking at whether reducing a protein called Glut1 can help prevent serious problems that can happen with diabetes, like eye, kidney, and nerve issues, using mice with both Type 1 and Type 2 diabetes to find better ways to manage the condition.
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Improving access to antimicrobial stewardship through videoconferencing
This study is exploring how video calls can help bring together a team of experts to better manage antibiotic use for Veterans, making it easier for them to get the care they need to avoid infections and resistance to medications.
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Restoring touch and movement for veterans with upper limb loss
This study is exploring a new way to help veterans who have lost an arm feel more connected to their prosthetic hands by using special nerve electrodes that can restore the sense of touch and make it easier to control their movements, so they can enjoy everyday activities more naturally.
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Using electrical stimulation to help bowel emptying after spinal cord injury
This study is testing a new way to use gentle electrical stimulation to help people with spinal cord injuries have better bowel movements, making it easier for them to manage their bowel care.
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Using a robotic arm brace to help stroke survivors regain arm movement
This study is testing a new way to help stroke survivors with limited arm movement get better using a special robotic device called MyoPro, combined with therapy that focuses on learning new movements, so participants can practice both in the clinic and at home.
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