NIH-funded research NIH-funded research

Nerve stimulation and wearable sensors to improve walking after partial spinal cord injury

Official title: Neural Stimulation to Enhance Community Mobility after Incomplete SCI

Funded at Louis Stokes Cleveland VA Medical Center · NIH-11222695 · Data updated 2026-11-12

Using wearable sensors and targeted nerve stimulation to help Veterans with incomplete spinal cord injury walk faster and more steadily so they can participate in community activities.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionLouis Stokes Cleveland VA Medical Center
NIH-funded
Lab location1 site (Cleveland, United States)
Project startJanuary 1, 2024
Project endDecember 31, 2027
Funding year2026
NIH project number5I01RX004246-03
Project IDNIH-11222695 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are Veterans with incomplete spinal cord injury who retain some voluntary leg movement, have trouble walking in the community, and can attend repeated training visits and consider implanted or external stimulation.

Less likely to help

People with complete spinal cord injuries, no voluntary leg control, or medical contraindications to implanted or surface stimulation are unlikely to benefit from this project.

What this research studies

You would first do conventional gait training and then take part in sessions where you walk with and without a stimulation controller while wearing a small set of body-mounted sensors. The team will use those sensors to drive peripheral nerve stimulation that augments weakened muscles in real time, helping your natural movements push you forward and recover from slips or trips. Ten people with incomplete spinal cord injury will each serve as their own control in single-subject comparisons, and six participants will receive implanted stimulators combined with externally worn sensors. Results will guide development of easier-to-use surface or fully implanted systems that could be used outside the clinic.

Why it matters

Potential benefit: If successful, this approach could let Veterans with incomplete spinal cord injury walk more safely and independently in their communities.

How similar studies have gone: Functional electrical stimulation and neuromodulation have helped some people with incomplete SCI walk and balance better, but this project’s real-time adaptive controller approach is a newer application of those methods.

Where this research is happening

  • Louis Stokes Cleveland VA Medical Center
    Cleveland, United States
    Active

Researchers

  • Principal investigator: Triolo, Ronald J — Louis Stokes Cleveland VA Medical Center
  • Study coordinator: Triolo, Ronald J

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.