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Clinical trials and research at Institut Curie

• 25Clinical trials
• 9Countries

Newest trials

All recruiting trials (25)

• Using enteral (tube) feeding as recommended for adults with cancer.

  This project will see how well enteral (tube) feeding recommendations are followed by adults hospitalized for cancer who need enteral nutrition.

  Recruiting Institut Curie · Paris · NCT07571564

• Home-capillary blood sampling to monitor CDK4/6 inhibitors in breast cancer

  This study tests whether fingertip capillary samples collected at home can reliably measure drug levels for breast cancer patients treated with ribociclib, abemaciclib, or palbociclib, compared with standard venous draws.

  Recruiting Institut Curie · Paris and 1 other locations · NCT07491380

• Screening and care for fear that breast or lung cancer will come back or get worse at Institut Curie

  This project will test brief screening methods to find people at Institut Curie with severe fear that their breast or lung cancer will come back or progress so they can get appropriate help.

  Recruiting Institut Curie · Paris · NCT07357311

• Tucatinib plus trastuzumab for HER3-mutant, HER2-not amplified metastatic breast cancer

  This trial will test whether combining tucatinib and trastuzumab helps people with metastatic or unresectable breast cancer whose tumors are HER2-negative but carry activating ERBB3 (HER3) mutations.

  Recruiting Phase 2 Institut Curie · Bordeaux and 8 other locations · NCT07193394

• Skin reactions from chest implantable port dressings

  This study will see how often dressings on chest implantable ports cause skin reactions in adults starting first-line chemotherapy.

  Recruiting Institut Curie · Paris and 2 other locations · NCT07158879

• PET-FAPI imaging to find pancreatic cancer earlier

  This will try a PET scan using a FAPI tracer to find early or returning pancreatic cancer in adults with recently diagnosed non‑metastatic PDAC who are enrolled in the HoMING cohort.

  Recruiting Phase 2 Institut Curie · Saint-Cloud · NCT06659705

• Personalized therapy using patient-derived organoids for metastatic breast cancer

  This study is testing whether using mini versions of a patient's breast tumor can help find the best treatment options for people with metastatic breast cancer.

  Recruiting at 2 sites Institut Curie · Paris and 2 other locations · NCT06459791

• Screening for bronchopulmonary cancer in a structured network

  This study is testing a new way to screen for lung cancer using special scans in a network of health centers to see if it helps catch the disease early.

  Recruiting at 4 sites Institut Curie · Bobigny and 8 other locations · NCT06439901

• Using PET/CT imaging to predict treatment response in triple-negative breast cancer

  This study is testing if a special type of imaging can help predict how well early-stage triple-negative breast cancer patients will respond to their treatment with pembrolizumab and chemotherapy.

  Recruiting at 6 sites Institut Curie · Antony and 5 other locations · NCT06349512

• Early detection of relapse in triple‑negative breast cancer using blood DNA and advanced PET imaging

  This study tests whether regular ctDNA blood checks combined with 68Ga‑FAPI‑46 and 18F‑FDG PET‑CT scans can find relapse earlier in people who finished treatment for high‑risk, non‑metastatic triple‑negative breast cancer.

  Recruiting Institut Curie · Avignon and 12 other locations · NCT06225505

• Using PET scans and biomarkers to guide treatment for metastatic breast cancer

  This study is testing if using special scans and blood tests can help doctors choose the best treatment for women with a specific type of advanced breast cancer.

  Recruiting at 10 sites Phase 3 Institut Curie · Bayonne and 20 other locations · NCT06195709

• Combination treatment for metastatic HER2-positive breast cancer

  This study is testing a new combination of medications for people with HER2-positive metastatic breast cancer who haven't responded to previous treatments, to see if it can help them feel better and manage their disease.

  Recruiting at 9 sites Phase 2 Institut Curie · Clermont-Ferrand, Clermont Ferrand and 12 other locations · NCT05955170

• Comparing Taurolidine and Saline Locks for Catheter Care in Children with Cancer

  This study tests whether using a Taurolidine lock instead of a regular saline lock can help prevent infections in central catheters for kids and young adults with cancer.

  Recruiting at 5 sites Institut Curie · Paris and 4 other locations · NCT05781295

• Characterizing immune features of thymic epithelial tumors

  This study is testing the immune features of thymic epithelial tumors in patients having surgery to see how these tumors behave and if new treatments can be developed.

  Recruiting at 3 sites Institut Curie · Paris and 2 other locations · NCT05558644

• Individualized nutrition and physical activity program for frail patients with advanced digestive cancers

  This study tests whether an 8-week program of personalized nutrition and exercise can help frail patients with advanced digestive cancers feel better during their first treatment.

  Recruiting at 8 sites Institut Curie · Tours, Institut Curie and 17 other locations · NCT05441163

• Comparing opioid-free and opioid-based anesthesia for breast reconstruction surgery

  This study is testing whether using an opioid-free anesthesia during breast reconstruction surgery can help women manage pain and recover better compared to traditional opioid-based anesthesia.

  Recruiting at 3 sites Phase 3 Institut Curie · Paris and 2 other locations · NCT05439005

• Exploring immune cells in cancer patients through blood sampling

  This study is testing how immune cells in the blood of cancer patients respond to treatment to help improve future therapies.

  Recruiting at 2 sites Institut Curie · Paris and 1 other locations · NCT05354765

• International registry and biobank for patients with peripheral neuroblastic tumors

  This study is setting up a global database and biobank for patients with peripheral neuroblastic tumors to gather important health information and samples that can help improve future treatments.

  Recruiting at 35 sites Institut Curie · Prague and 37 other locations · NCT05192980

• Analysis of blood biomarkers in cancer patients

  This study is testing how blood samples from cancer patients can help doctors better understand and treat their cancer.

  Recruiting at 2 sites Institut Curie · Paris and 1 other locations · NCT05088395

• Using liquid biopsy to predict responses to immunotherapy in metastatic lung cancer

  This study is testing if measuring tumor DNA in the blood can help predict how well new immunotherapy treatments work for people with advanced lung cancer who haven't started treatment yet.

  Recruiting at 3 sites Institut Curie · Boulogne-Billancourt and 2 other locations · NCT04790682

• Comparing radiotherapy and surveillance after thymoma surgery

  This study is testing whether getting radiation therapy after thymoma surgery helps prevent the cancer from coming back better than just keeping an eye on things without treatment.

  Recruiting at 14 sites Institut Curie · Caen and 20 other locations · NCT04731610

• New treatments for retinoblastoma to improve vision outcomes

  This study is testing new treatment options for children with retinoblastoma to see if they can improve vision and control the disease better than current methods.

  Recruiting at 28 sites Phase 2/3 Institut Curie · Saint-Denis, La Réunion and 27 other locations · NCT04681417

• Monitoring patients with uveal melanoma for liver metastases

  This study is testing a special follow-up plan with regular liver scans and blood tests for people with uveal melanoma to see if it helps catch liver cancer spread early.

  Recruiting Institut Curie · Paris · NCT04424719

• Biobanking study to understand cancer and immune response

  This study is collecting tumor and blood samples from cancer patients to see how their tumors and immune responses change during treatment.

  Recruiting at 5 sites Institut Curie · Bordeaux and 5 other locations · NCT03017573

• Classifying genetic variants for cancer risk assessment

  This study is testing how to better understand certain genetic changes in cancer-related genes to help patients and their families make informed decisions about their cancer risk and treatment options.

  Recruiting at 55 sites Institut Curie · Bastia, Corsica and 61 other locations · NCT01689584

Quick answers

How many clinical trials run by Institut Curie are recruiting right now?

25, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in France (25 trials), Guadeloupe (1 trial), Martinique (1 trial), New Caledonia (1 trial), Reunion (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 3, Phase 3: 2, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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