Skin reactions from chest implantable port dressings

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, multicenter observational cohort enrolling 500 adults starting first-line systemic chemotherapy who receive a thoracic implantable catheter chamber (ICC/PAC). Investigators will follow patients at participating centers to record skin reactions at the dressing site, such as persistent redness, itching, or dermabrasion, and measure the incidence of these events. The protocol excludes PICC or femoral lines, hematologic cancers, and patients receiving certain bi-specific antibody treatments. No experimental treatments are given; the study collects real-world data on current dressing practices across sites including Paris and French Polynesia.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients over 18 years of age
* New chemotherapy patients (1st line of treatment only)
* Thoracic PAC

Exclusion Criteria:

* PICC Line and femoral PAC;
* Patients undergoing treatment with bi-specific antibodies (e.g. tebentafusp);
* Disunion requiring treatment
* Patients treated for hematological cancer;
* Persons deprived of their liberty or under guardianship (including curatorship);
* Adults under court protection;
* Inability to participate in the study for geographical, social or psychological reasons.
* No inclusion of persons covered by articles L. 1121-5 to L. 1121-8 and L. 1122-1-2 of the French Public Health Code (e.g. minors, protected adults, etc.).
* Opposition to data use

Where it's running

• Institut Curie
  Paris, France Recruiting
• Centre Hospitalier de Polynésie Française CHPF
  Pirae, French Polynesia Not yet recruiting
• Hôpital Uturoa
  Uturoa, French Polynesia Not yet recruiting

Study contacts

• Principal investigator: Betty LIMIER — Institut Curie
• Study coordinator: Betty LIMIER
• Email: betty.limier@curie.fr
• Phone: +33 1 44 32 43 65

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Does driving with UVA exposure affect facial skin hydration on the left vs right cheek in Florida drivers

  This observational study tests whether Florida women who drive more show less hydration on their left cheek (exposed to UVA through the driver-side window) compared with their right cheek.

  Recruiting IAS Skin Care · Orlando, Florida · NCT07764809

• Topical KB111 for Hailey-Hailey Disease (early phase, kids and adults)

  This study tests whether a topical KB111 treatment is safe and helps with lesions in people with Hailey-Hailey disease, including adolescents and adults.

  Recruiting Early Phase 1 Krystal Biotech, Inc. · Miami, Florida · NCT07717346

• Turning anonymous symptom descriptions into structured biological signals with OpenGenome

  This project tries to turn adults' anonymous free-text symptom descriptions submitted to OpenGenome into structured, literature-grounded biological signals using PubMed and ClinicalTrials.gov sources and a constrained reasoning model.

  Recruiting OpenGenome · Friedrichshain, State of Berlin · NCT07578610

• Safety of BG-A3004 in healthy volunteers and people with immune-mediated skin diseases

  This study will test whether single and multiple doses of the experimental drug BG-A3004 are safe and how the body handles it in healthy adults and people with immune-mediated skin diseases.

  Recruiting at 11 sites Phase 1 BeOne Medicines · Beijing, Beijing Municipality and 10 other locations · NCT07412691

• Detailed profiling of chronic inducible urticaria (symptomatic dermographism and cold urticaria)

  This project will test whether detailed biological and skin measurements can find markers to help diagnose and predict treatment response in adults with symptomatic dermographism or cold urticaria.

  Recruiting at 2 sites Centre for Human Drug Research, Netherlands · Leiden, South Holland and 2 other locations · NCT07359430

• Objective measurement of skin pigmentation with colorimetry and multispectral imaging

  We will test whether non-invasive imaging (colorimetry, multispectral imaging, and line-field confocal OCT) can provide reliable, objective skin pigmentation measurements for adults with healthy skin or skin conditions.

  Recruiting Leiden University Medical Center · Leiden, Leiden · NCT07091604

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.