Sponsor or institution

Clinical trials and research at Doheny Eye Institute

• 13NIH research projects

NIH-funded research (13)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Early biomarkers and imaging markers to predict AMD progression

  This project looks at how advanced eye imaging and biomarkers can identify which people with early age-related macular degeneration are likely to progress, so future treatments can be tested sooner.

  NIH research Doheny Eye Institute · Pasadena, UNITED STATES · NIH-11398025

• Retina-derived extracellular vesicles and diabetic retinopathy: possible roles in disease and therapy

  Tiny vesicles from retinal cells may drive inflammation and damage in diabetic retinopathy, and this research looks at how they form, carry signals, and could be targeted for treatment.

  NIH research Doheny Eye Institute · Pasadena, UNITED STATES · NIH-11389481

• Tiny particles from the retina and diabetic eye disease

  This research looks at whether tiny particles released by retinal cells drive blood-vessel damage in diabetic retinopathy and could point to new treatments for people with diabetes-related vision loss.

  NIH research Doheny Eye Institute · Pasadena, UNITED STATES · NIH-11375541

• Retinal nerve signals and energy: how your eye cells talk when energy changes

  A study at the Dohoeny Eye Institute will look at how retinal ganglion cells respond to light when their energy balance changes, to better understand conditions that can lead to vision loss.

  NIH research Doheny Eye Institute · Pasadena, UNITED STATES · NIH-11308667

• High-resolution molecular imaging of the retina

  A new high-resolution eye imaging method that looks at tiny molecular signals in the retina to spot early changes linked to aging and macular degeneration.

  NIH research Doheny Eye Institute · Pasadena, UNITED STATES · NIH-11290385

• Early signs that predict worsening of age-related macular degeneration

  This project looks at modern eye scans to find early signs that show whether people with age-related macular degeneration will get worse.

  NIH research Doheny Eye Institute · Pasadena, UNITED STATES · NIH-11170593

• Measuring tiny blood flow and pulsation in retinal capillaries

  Using a high-resolution adaptive optics camera to watch how red blood cells move in tiny retinal vessels for people with or at risk for retinal or vascular eye disease.

  NIH research Doheny Eye Institute · Pasadena, UNITED STATES · NIH-11145937

• Investigating how energy levels affect signaling in retinal ganglion cells

  This study looks at how the energy levels in our body affect the way important eye cells, called retinal ganglion cells, respond to light, which could help us understand why some people lose their vision and find new ways to treat it.

  NIH research Doheny Eye Institute · Pasadena, UNITED STATES · NIH-11075372

• Imaging the human retina to understand aging and eye diseases

  This study is looking at how advanced imaging can help us see the health of the retina in people with age-related macular degeneration (AMD), which could lead to better treatments for this eye condition.

  NIH research Doheny Eye Institute · Pasadena, UNITED STATES · NIH-11041079

• Understanding genetic factors in age-related macular degeneration

  This study is looking at how certain genes might affect the way your eyes respond to stress as they age, which could help us understand age-related macular degeneration (AMD) better and lead to more personalized treatments for patients like you.

  NIH research Doheny Eye Institute · Pasadena, UNITED STATES · NIH-10925181

• Investigating biomarkers for early intervention in age-related macular degeneration

  This study is looking for early signs of age-related macular degeneration (AMD) using special imaging tools, so that people can get the right help sooner and potentially slow down the disease.

  NIH research Doheny Eye Institute · Pasadena, UNITED STATES · NIH-10914769

• Understanding blood flow in the retina

  This study is looking at how blood moves through the tiny vessels in your eyes to help keep your vision healthy, and it’s for anyone interested in understanding eye health and how to prevent eye diseases.

  NIH research Doheny Eye Institute · Pasadena, UNITED STATES · NIH-10898631

• Investigating mitochondrial defects and genetic factors in age-related macular degeneration

  This study is looking at how problems in tiny parts of cells called mitochondria might lead to age-related macular degeneration (AMD), a common cause of vision loss in older people, especially focusing on a specific gene that could increase the risk for this condition.

  NIH research Doheny Eye Institute · Pasadena, UNITED STATES · NIH-10874602

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