Investigating biomarkers for early intervention in age-related macular degeneration

Epidemiology of Biomarkers of AMD Progression

NIH-funded research Doheny Eye Institute · NIH-10914769

This study is looking for early signs of age-related macular degeneration (AMD) using special imaging tools, so that people can get the right help sooner and potentially slow down the disease.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionDoheny Eye Institute NIH-funded
Lab location1 site (Pasadena, UNITED STATES)
Project IDNIH-10914769 on NIH RePORTER

What this research studies

This research focuses on identifying biomarkers that can help detect early stages of age-related macular degeneration (AMD) before it progresses to more severe forms. By utilizing advanced imaging technologies like optical coherence tomography (OCT) and OCT angiography, the study aims to create a more detailed staging system for AMD. This could allow for timely interventions that could prevent or slow down the progression of the disease. The research seeks to refine patient selection for clinical trials based on these biomarkers, ultimately improving treatment outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals at risk for age-related macular degeneration, particularly those in the early stages of the disease.

Not a fit: Patients who have already progressed to late-stage age-related macular degeneration may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier and more effective treatments for patients with age-related macular degeneration.

How similar studies have performed: Previous studies have shown promise in using advanced imaging techniques to assess AMD, suggesting that this approach could yield valuable insights.

Where this research is happening

Pasadena, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.