Investigating biomarkers for early intervention in age-related macular degeneration
Official title: Epidemiology of Biomarkers of AMD Progression
Funded at Doheny Eye Institute · NIH-10914769 · Data updated 2026-11-12
This study is looking for early signs of age-related macular degeneration (AMD) using special imaging tools, so that people can get the right help sooner and potentially slow down the disease.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Doheny Eye Institute NIH-funded |
| Lab location | 1 site (Pasadena, UNITED STATES) |
| Project start | September 30, 2021 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $585,469 |
| NIH project number | 5R01EY030614-03 |
| Project ID | NIH-10914769 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals at risk for age-related macular degeneration, particularly those in the early stages of the disease.
✕Less likely to help
Patients who have already progressed to late-stage age-related macular degeneration may not benefit from this research.
What this research studies
This research focuses on identifying biomarkers that can help detect early stages of age-related macular degeneration (AMD) before it progresses to more severe forms. By utilizing advanced imaging technologies like optical coherence tomography (OCT) and OCT angiography, the study aims to create a more detailed staging system for AMD. This could allow for timely interventions that could prevent or slow down the progression of the disease. The research seeks to refine patient selection for clinical trials based on these biomarkers, ultimately improving treatment outcomes.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more effective treatments for patients with age-related macular degeneration.
How similar studies have gone: Previous studies have shown promise in using advanced imaging techniques to assess AMD, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Doheny Eye Institute
Pasadena, United States Active
Researchers
- Principal investigator: Sadda, Srinivas R — Doheny Eye Institute
- Study coordinator: Sadda, Srinivas R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.