Imaging the human retina to understand aging and eye diseases
In vivo Imaging of the Human Retina at the Molecular Level
This study is looking at how advanced imaging can help us see the health of the retina in people with age-related macular degeneration (AMD), which could lead to better treatments for this eye condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Doheny Eye Institute NIH-funded |
| Lab location | 1 site (Pasadena, UNITED STATES) |
| Project ID | NIH-11041079 on NIH RePORTER |
What this research studies
This research focuses on using advanced imaging techniques to observe the human retina at a molecular level, particularly in relation to age-related macular degeneration (AMD). By employing fluorescence lifetime imaging ophthalmoscopy (FLIO) combined with adaptive optics, the study aims to measure the metabolic status and oxidative stress in retinal cells. This innovative approach will allow for detailed analysis of the retina's health and could lead to better understanding and treatment of age-related eye conditions. Patients may benefit from insights gained through this imaging technology, which could inform future therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing symptoms of age-related macular degeneration or those at risk due to age or genetic factors.
Not a fit: Patients with retinal conditions unrelated to aging or those who do not have access to the imaging technology may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatments for age-related macular degeneration and other retinal diseases.
How similar studies have performed: Previous research using similar imaging techniques has shown promise in understanding retinal diseases, suggesting that this approach could yield valuable insights.
Where this research is happening
Pasadena, UNITED STATES
- Doheny Eye Institute — Pasadena, United States (Active)
Researchers
- Principal investigator: Sadda, Srinivas R — Doheny Eye Institute
- Study coordinator: Sadda, Srinivas R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.