Sponsor or institution
Clinical trials and research at Baltimore VA Medical Center
As of November 12, 2026, Find a Trial lists 68 NIH-funded research projects at this institution. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 68NIH research projects
NIH-funded research (newest 40 of 68)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Co-Targeting IL-6 and CDK4/6 to Prevent TNBC in Women Veterans
A study aims to block two cancer-promoting pathways (IL-6 and CDK4/6) to prevent or reduce progression of triple-negative breast cancer in women veterans.
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Modifying body fat to aid COVID-19 recovery through behavioral strategies
A study in veterans explores whether changing weight through lifestyle habits can improve recovery after COVID-19–related health problems.
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A Balanced Reach Training Platform to Help Balance in Older Veterans
A new training program uses balance challenges to improve posture and movement in older veterans who are at risk of falls.
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Home-based exercise to help Veterans recover after healed diabetic foot ulcers
A home-based exercise program for Veterans who recently healed from a diabetic foot ulcer to improve walking and daily function.
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Cognitive Behavioral Therapy for Insomnia to Help Veterans with Psychosis
A veteran-focused CBT-I program tailored for those with psychosis aims to improve sleep and daily functioning.
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Balanced Reach Training to Improve Balance for Older and Neurologically Disabled Veterans
This project uses a progressive reach‑at‑your‑limits training program to help older and neurologically disabled Veterans strengthen balance and lower fall risk.
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Genetic testing to find causes of early-onset ischemic stroke
This project uses whole-exome sequencing to look for gene changes that may cause ischemic stroke in adults who had a stroke at a young age.
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Reducing Fall Risk with Hip Hip Abductor Stimulation During Balance Training
This project tests whether using electrical stimulation on the hip abductors during balance training helps older veterans improve balance and reduce fall risk.
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Why some immune T cells may let lung cancer grow
This work looks at whether a common immune cell (CD8+ T cell) can make the body tolerate lung cancer, aiming to help people with lung cancer get more effective immunotherapy.
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Calorie reduction to support long-term recovery after traumatic brain injury
A controlled calorie-reduction approach to help people with past traumatic brain injury regain lasting neurological function.
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PTSD Treatment for Veterans with Serious Mental Illness to Improve Function
A pilot program tests a PTSD treatment adapted for veterans who also have serious mental illness to see if it’s usable and acceptable and could improve daily functioning.
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Electrical stimulation plus a drug to reduce muscle fat and wasting after a rotator cuff tear
This work tests whether gentle electrical pulses together with a medicine that blocks PDGFRα can prevent fatty change and muscle wasting after a torn rotator cuff to help people with large shoulder tendon injuries.
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Home exercise and remote rehabilitation for veterans recovering from COVID-19
A home-based exercise program with group video sessions designed to help veterans recovering from COVID-19 rebuild heart, lung, and overall physical strength.
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Using targeted gloves and gowns to prevent MRSA spread in hospitals
This project tests whether using gloves and gowns only for certain patients and encounters can reduce MRSA spread among hospital patients.
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Brain-targeted estradiol therapy for stress-related mental health in Veterans
Researchers are developing a brain-targeted form of estradiol to help Veterans with depression, anxiety, and PTSD.
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Investigating how stem cells help ligaments heal and regenerate
This study is looking at how special cells around blood vessels can help heal ligament injuries, like ACL tears, especially in veterans who often face these kinds of injuries, with the goal of finding better treatments to improve recovery after surgery.
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Targeting arthritis treatment using special peptides in a mouse model
This study is exploring a new way to help people with rheumatoid arthritis by using a special delivery system to send a powerful anti-inflammatory medicine right to the joints that hurt, aiming to make treatment more effective and reduce side effects, especially for U.S. Veterans.
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Targeted immune-metabolism treatment for veterans with multiple sclerosis
This project develops a biomaterials-based way to deliver immune-changing medicines to veterans with multiple sclerosis to reduce harmful inflammation while keeping normal immune defenses intact.
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How IL‑33 and ST2 drive tissue scarring (fibrosis)
This project looks at how two immune molecules, IL‑33 and its receptor ST2, may cause harmful scarring in organs to help people with inflammatory and fibrotic diseases.
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Teaching the immune system to tolerate myelin
Researchers are developing vaccine-like treatments to train the immune system not to attack myelin in people with multiple sclerosis.
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Improving day-to-day functioning for mid-life and older women Veterans
This project adapts a cognitive-behavioral therapy to help mid-life and older women Veterans manage menopause-related symptoms and improve everyday functioning.
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Improving sleep for veterans with psychosis using therapy
This study is testing a special sleep therapy called Cognitive Behavioral Therapy for Insomnia (CBT-I) to help veterans with psychosis get better sleep and feel more functional in their daily lives.
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Reducing unnecessary antibiotic use for urinary tract infections
This study is looking at ways to better diagnose urinary tract infections (UTIs) so that people don’t get prescribed antibiotics they don’t need, helping to keep antibiotics effective for everyone.
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CD34+ Melanocyte Stem Cells: A New Path to Neuroprotection and Melanoma Insight
A study from the Baltimore VA Medical Center explores a special skin stem cell that may help repair nerve damage and influence melanoma treatment.
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Multispecific antibodies to fight HIV-1 in people
A new approach uses engineered multispecific antibodies to target HIV-1 in people, aiming to improve prevention and treatment options.
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Improving PTSD treatment for veterans with serious mental illness
This study is looking to improve treatment for veterans dealing with PTSD and serious mental health issues by trying out a new approach that includes their cultural identity, to see if it helps them feel better and live better lives.
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Improving recovery from COVID-19 by addressing obesity
This study is looking at how losing weight can help older Veterans who are recovering from COVID-19 feel better and improve their health, and it’s designed for those who have been affected by the virus and want to enhance their recovery.
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A training program to improve balance in older veterans
This study is testing a new training program designed to help older veterans improve their balance and reduce their risk of falling by practicing reaching tasks that challenge their stability in a safe way.
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Investigating how to enhance intestinal healing and integrity after injury.
This study is looking at how to help the gut heal after injury, especially for people who are very sick, by exploring new treatments that could improve gut health and function.
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Home exercise program to help Veterans recover after a recently healed diabetic foot ulcer
A home-based exercise program designed to help Veterans who recently healed from a diabetic foot ulcer regain strength, mobility, and independence.
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Better drug delivery for breast cancer that has spread to the brain
New methods to deliver cancer-fighting drugs into the brain for people whose breast cancer has spread there.
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CBT for chronic pain in veterans with serious mental illness
A government-funded program tests whether a talk-based therapy called CBT-CP helps veterans who have both chronic pain and serious mental illness feel better and function more normally.
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Investigating how alcohol abuse during late adolescence affects combat Veterans' health.
This study looks at how heavy drinking during the teenage years might affect the health of veterans later on, especially in areas like decision-making and emotions, to help find better ways to prevent and treat issues like addiction, depression, and PTSD in those who served.
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New treatments for severe lung inflammation in older adults
This study is working on new medications to help people with Acute Respiratory Distress Syndrome (ARDS), especially those who have had respiratory infections like COVID-19, by creating drugs that can reduce harmful inflammation in the lungs while keeping the good stuff intact.
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Using estradiol to treat stress-related mental health issues in Veterans
This study is looking at how a hormone called estradiol might help improve mental health for Veterans dealing with stress-related issues like depression and PTSD, by exploring how it works in the brain and aiming to create a safer treatment option.
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Using nanotechnology to promote immune tolerance in Multiple Sclerosis
This study is exploring a new way to help people with Multiple Sclerosis by using tiny particles to improve how the body delivers signals that calm down the immune system, helping to protect the nerves from damage while still keeping the good parts of the immune response.
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Investigating how a viral protein affects brain inflammation and damage in HIV patients
This study is looking at how a specific HIV protein might cause brain inflammation and related mental health issues, like depression, in people living with HIV, especially veterans, to find new ways to help improve their well-being.
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Creating a new animal model to study post-traumatic epilepsy
This study is creating a new way to test treatments for post-traumatic epilepsy in rats, which could help find better options for people living with this condition.
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Training healthcare providers in data science for better care of aging veterans
The SUMMERDSSRWHAV Program at the Baltimore VA Medical Center is a friendly training program for future healthcare providers and researchers, helping them learn how to use VA data to improve the health of veterans, especially older ones, through an eight-week course focused on teamwork and ethical research practices.
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Using machine learning to assess and manage the risk of blood clots in hospitalized patients.
This study is working on a new tool to help doctors better prevent blood clots in hospitalized Veterans by using smart technology to understand each patient's risk and preferences, making sure they get the best care possible.
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