Investigating how to enhance intestinal healing and integrity after injury.
Official title: BLRD Research Career Scientist Award Application
Funded at Baltimore VA Medical Center · NIH-11165160 · Data updated 2026-11-12
This study is looking at how to help the gut heal after injury, especially for people who are very sick, by exploring new treatments that could improve gut health and function.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baltimore VA Medical Center NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | April 1, 2018 |
| Project end | March 31, 2032 |
| Funding year | 2025 |
| NIH project number | 2IK6BX004213-08 |
| Project ID | NIH-11165160 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include patients with critical illnesses that affect gut health and those experiencing intestinal injuries.
✕Less likely to help
Patients with stable gastrointestinal conditions or those not experiencing any intestinal injury may not benefit from this research.
What this research studies
This research focuses on understanding the mechanisms that promote the regeneration of the intestinal lining after injury, particularly in patients facing critical illnesses. Dr. Jian-Ying Wang's team studies the role of long noncoding RNAs and RNA-binding proteins in maintaining gut health and explores new therapies aimed at improving mucosal repair. By utilizing advanced biological models, the research aims to identify effective strategies to enhance gut permeability and overall intestinal function.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for patients with intestinal injuries, enhancing their recovery and quality of life.
How similar studies have gone: Previous research has shown promising results in enhancing intestinal healing through targeted therapies, indicating that this approach has potential for success.
Where this research is happening
-
Baltimore VA Medical Center
Baltimore, United States Active
Researchers
- Principal investigator: Wang, Jian-Ying — Baltimore VA Medical Center
- Study coordinator: Wang, Jian-Ying
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.