Sponsor or institution
Clinical trials and research at Allen Institute
As of November 12, 2026, Find a Trial lists 75 NIH-funded research projects at this institution, with $193.3 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 75NIH research projects
NIH-funded research (newest 40 of 75)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Light Pipe Microscope for ultra-large-scale brain imaging
A new, lighter and cheaper microscope tool could help researchers image brain activity across large areas of the mouse brain in cellular detail.
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Panoramic, minimally invasive deep-brain imaging interface for broad neural access
A new imaging tool in deep brain areas aims to let scientists see large brain regions at cellular detail with a tiny, minimally invasive probe.
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SPOCTT 2.0: Understanding Brain Cell Types with AI and Maps
A national brain-research program is creating user-friendly tools and references to map brain cell types, making it easier for scientists and students to explore brain cells in humans and animals.
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Large brain circuit models run on supercomputers
Aims to create and share powerful computer models of huge brain circuits to understand how thinking and behavior emerge in diseases like Alzheimer’s.
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Spatial map of Alzheimer's cell types and disease patterns
Researchers are using advanced spatial genomics to map where different brain cells and disease markers sit in Alzheimer's and related dementias, with the goal of understanding what goes wrong in the brain.
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Single-cell brain study of Alzheimer's disease across regions
A large NIH project will map the cellular and molecular changes in the brains of people with Alzheimer's disease using cutting-edge single-cell genomics.
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Brain donor network to advance Alzheimer's and related dementias tissue research
A NIH-funded network will build a large, well-characterized collection of donated brains from people with Alzheimer’s and related dementias to enable advanced tissue analysis.
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Alzheimer's Disease Cell Atlas and Data Hub for Integrated Brain Pathology and Omics
A nationwide effort to map brain cells and molecular data in Alzheimer’s and related dementias to create a shared, searchable resource for researchers and patients alike.
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Atlas of brain cells in Alzheimer’s and related dementias
A large research effort is creating a detailed map of brain cells and molecules affected by Alzheimer's disease and related dementias to help scientists understand and eventually treat these conditions.
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Brain cell atlas for Alzheimer's disease and related dementias
A large-scale project will map brain cells and their gene activity in people with Alzheimer's and related dementias to help researchers understand what goes wrong.
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Center for a scalable pipeline to map the mouse brain’s wiring with advanced microscopy
A patient-friendly center aims to map the complete wiring diagram of the mouse brain using high-throughput, advanced imaging to better understand how brain cells connect.
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BRAIN CONNECTS: Linking brain cell types to their wiring across scales using light microscopy
This grant supports a large study to map brain cell types and how they connect across the whole mammalian brain using new light-m microscopy methods.
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Open-source light-sheet microscope to image big tissue samples
A new open-source light-sheet microscope (LS2) aims to image tissue from tiny cells to whole organs at high resolution, helping researchers study brain structure.
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Functionally guided cell atlas of the human and primate brain
A large NIH project will map brain cells in humans and non-human primates to better understand how the brain is organized and how diseases affect it.
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How brain networks shape actions to reach rewards
This project studies how brain activity patterns are re-created to drive purposeful actions that lead to desired outcomes.
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Virtual Observatory of the Cortex for brain cells, circuits, and dynamics
A project to create a centralized, user-friendly platform that shares a huge mouse brain dataset with detailed cell structures, connections, and activity in real time for researchers and clinicians.
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A shared brain cell map resource for researchers
A large, collaborative project to create a detailed map of brain cell types in humans and primates to help scientists understand brain health and disease.
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Brain cell knowledge base and toolset for multi-species data-driven cell types
Aims to build an extensible brain cell knowledge base that combines data from mouse, human, and primates to create a public, interactive resource for understanding brain cell types.
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Oligonucleotide therapy to raise NaV1.1 protein in Dravet syndrome
A new antisense therapy aims to boost the brain’s NaV1.1 protein to help people with Dravet syndrome.
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A platform to reveal how cells boost hormone secretory efficiency
A research team at the Allen Institute is building a general method to uncover cellular processes that make hormone secretion more efficient, with potential relevance to bipolar disorder and diabetes.
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Investigating innovative approaches to improve health outcomes.
This study is looking for new ways to improve care and treatment for patients, so if you're dealing with a health issue, you might have a chance to try out some exciting new methods that could help you feel better.
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Investigating innovative approaches to improve health outcomes.
This study is looking for new ways to improve care and treatment for patients like you, and you might have the chance to try out some of these exciting new methods to help make you feel better.
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How HIV and long-term cocaine use change brain cells
Researchers will look at how HIV infection and chronic cocaine use alter gene activity and DNA accessibility in brain cells to better understand brain problems in people living with HIV who use cocaine.
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How genes shape connections between the brain's cortex and thalamus
This project maps which genes are linked to long-distance connections between brain regions in adults to improve understanding of how the adult brain is wired.
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Understanding the Brain's Wiring and Activity
This project is creating a detailed map of brain cells and their connections to help us better understand how the brain works.
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Exploring how a protein affects immune cells that fight melanoma
This study is looking at how a protein called Fgl2 affects immune cells that help fight melanoma, a serious skin cancer, to find ways to make cancer treatments work better for patients.
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Understanding deep-layer brain nerve cells and how they are controlled
This work looks at how specific deep-layer brain cells in humans and primates respond to ion channels and chemical signals, with implications for people with Alzheimer's and related brain disorders.
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A detailed cell map of the adult human and primate brain
Building a detailed map of cell types across adult human and primate brains to help people with brain disorders.
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Mapping the Different Types of Cells in the Brain
This project is creating a detailed map of all the different cell types in the human and primate brain, which will help us better understand how the brain works in health and disease.
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Creating a new treatment for Dravet syndrome
This study is exploring a new treatment for Dravet syndrome, a serious type of epilepsy that starts in babies, by developing a special therapy that helps boost a key protein in the brain to reduce seizures and improve survival, with plans to test it in animals first before moving to people.
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A comprehensive map of brain cells across different species
This project is building a comprehensive database to organize and share detailed information about brain cells from humans and other species.
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Creating tools to target specific brain cell types using viruses.
This study is all about creating special tools to help scientists target and understand different types of brain cells in mice and monkeys, which could lead to better treatments for brain-related conditions.
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A detailed map of brain cells in Alzheimer's and related dementias
Building a comprehensive, publicly shared map of how brain cell types and their molecular signatures change in people with Alzheimer's and related dementias to help researchers find new targets and tests.
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A platform for scientists to explore brain function using advanced imaging techniques
This study is creating a helpful online tool called OpenScope that lets scientists explore how the brain works using special imaging techniques, so they can share their findings and learn more about brain function together.
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Investigating how HIV and cocaine affect brain cells at a single-cell level
This study is looking at how HIV and cocaine addiction affect brain cells in mice, hoping to find new ways to help people with both conditions.
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Mapping the different types of norepinephrine and serotonin neurons in the brain
This study is looking at different types of brain cells that use norepinephrine and serotonin, which are important for how we think and act, to help us understand how they affect our choices and behaviors, and this could lead to better treatments for mood disorders.
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Improving brain modeling tools for better understanding of brain function
This study is working on new software to help scientists better understand how the brain works by creating realistic models that show brain activity, which can lead to improved research and insights about brain connections and behavior.
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Investigating and correcting brain circuitry using targeted viral tools
This study is exploring new ways to use special viruses to target and change specific brain cells, which could help us understand how these cells work and lead to better treatments for conditions like epilepsy.
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Mapping the complex connections of the brain
This study is all about mapping the connections in the brain to help us understand how it works and affects our feelings and actions, and it's for anyone interested in how our brains function, including people with different brain conditions.
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Measuring how brain cells process signals with large-scale neurotransmitter imaging
Scientists are developing new imaging tools to map how individual brain neurons integrate thousands of signals and produce outputs in behaving mice.
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