WePrEP: A bilingual tool to help transgender women and their providers pick the best PrEP method
Official title: WePrEP: A bilingual shared decision-making tool to facilitate conversations between transgender women and their providers as they select an ideal PrEP method
Funded at University of Colorado Denver · NIH-11378147 · Data updated 2026-11-12
A bilingual digital tool helps transgender women talk with their healthcare providers to choose between oral and injectable PrEP in a way that fits their needs and lifestyle.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project start | May 1, 2024 |
| Project end | February 28, 2027 |
| Funding year | 2026 |
| Award (this year) | $222,197 |
| NIH project number | 5R34MH136932-03 |
| Project ID | NIH-11378147 on NIH RePORTER |
Who could benefit from this research
✓Could help
Transgender women and other women at risk for HIV who are considering PrEP options and interacting with PrEP providers.
✕Less likely to help
Women who are not considering PrEP or do not engage with PrEP services may not benefit directly.
What this research studies
This project creates and tests a bilingual, patient-friendly decision aid called WePrEP to support conversations about HIV prevention. It focuses on cisgender and transgender women who are evaluating PrEP options, including long-acting injectable cabotegravir. The team will pilot the tool with providers and patients to see how well it supports shared decision making and improves communication about pregnancy, lactation, and adherence considerations. The study will measure usability, acceptability, and potential impact on choosing an optimal PrEP method.
Why it matters
Potential benefit: If successful, WePrEP could help more women make informed PrEP choices and improve adherence by aligning prevention methods with their values and life circumstances.
How similar studies have gone: Related decision-support tools have shown promise in improving patient-provider communication, but this project tailors to women’s specific PrEP decisions and bilingual needs.
Where this research is happening
-
University of Colorado Denver
Aurora, United States Active
Researchers
- Principal investigator: Rael, Christine Tagliaferri — University of Colorado Denver
- Study coordinator: Rael, Christine Tagliaferri
Related research
Other NIH-funded projects on the same topics.
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Improving HIV prevention counseling for women in family planning clinics
This study is working to help women make better choices about HIV prevention by creating a helpful tool for family planning clinics, making it easier for them to access options like PrEP.
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Improving access to PrEP for women during contraceptive counseling
This study is looking to help women get better information about PrEP during their family planning visits by creating a helpful guide that makes it easier to understand their options, so they can make informed choices about their health.
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Helping pregnant and breastfeeding women in Zambia make informed decisions about HIV prevention
This study is all about helping pregnant and breastfeeding women in Zambia make informed choices about using a medication called PrEP to prevent HIV, by encouraging open conversations that take their personal feelings and needs into account.
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Understanding how octopuses integrate sensory information and make decisions
This study is exploring how octopuses use their arms to grip things by looking closely at their nervous system and movements, which could help us understand their amazing abilities better.
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NoviGuide for Newborn Care in Pakistan
A small NIH grant to test a pocket-sized decision support tool for nurses and doctors to improve newborn care in Pakistan.
-
mChoice: Boosting PrEP Use and Adherence for Black and Latino MSM with Tailored Training and Support
A national study to help Black and Latino men who have sex with men start and stick with PrEP through culturally matched provider training and patient support.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.