Helping pregnant and breastfeeding women in Zambia make informed decisions about HIV prevention
Official title: Promoting PrEP shared decision-making and adherence among pregnant and breastfeeding women in Zambia
Funded at Univ of North Carolina Chapel Hill · NIH-10742941 · Data updated 2026-11-12
This study is all about helping pregnant and breastfeeding women in Zambia make informed choices about using a medication called PrEP to prevent HIV, by encouraging open conversations that take their personal feelings and needs into account.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project start | December 17, 2019 |
| Project end | November 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $181,247 |
| NIH project number | 5K01MH121186-05 |
| Project ID | NIH-10742941 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are pregnant and breastfeeding women in Zambia who are at risk of HIV.
✕Less likely to help
Patients who are not pregnant or breastfeeding, or those who are not at risk of HIV, may not benefit from this research.
What this research studies
This research focuses on improving the decision-making process for pregnant and breastfeeding women in Zambia regarding the use of pre-exposure prophylaxis (PrEP) to prevent HIV. It aims to develop and evaluate behavioral interventions that promote person-centered discussions about PrEP, ensuring that women's values and preferences are considered. The study will involve identifying key factors that influence women's decisions about PrEP through a mixed methods approach, which includes both qualitative and quantitative data collection. By enhancing shared decision-making, the research seeks to improve adherence to PrEP among this vulnerable population.
Why it matters
Potential benefit: If successful, this research could lead to better-informed decisions and increased adherence to HIV prevention methods among pregnant and breastfeeding women.
How similar studies have gone: Previous research has shown that person-centered approaches in healthcare can significantly improve patient adherence and outcomes, suggesting potential success for this approach.
Where this research is happening
-
Univ of North Carolina Chapel Hill
Chapel Hill, United States Active
Researchers
- Principal investigator: Hill, Lauren — Univ of North Carolina Chapel Hill
- Study coordinator: Hill, Lauren
Related research
Other NIH-funded projects on the same topics.
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CAB-LA PrEP for breastfeeding women after delivery in Botswana
This study tests a long-acting HIV prevention shot for new mothers who are breastfeeding in Botswana to see if it prevents HIV safely and effectively.
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CAB-LA PrEP for new mothers: safer HIV prevention for breastfeeding women in Botswana
A study tests a long-acting HIV prevention injection for breastfeeding women who are at high risk of HIV in Botswana.
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Long-acting injectable HIV prevention for breastfeeding mothers
This project offers long-acting injectable cabotegravir to high-risk breastfeeding women starting at delivery, with follow-up through post-partum and baby-care clinics to prevent HIV.
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WePrEP: A bilingual tool to help transgender women and their providers pick the best PrEP method
A bilingual digital tool helps transgender women talk with their healthcare providers to choose between oral and injectable PrEP in a way that fits their needs and lifestyle.
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Improving HIV prevention counseling for women in family planning clinics
This study is working to help women make better choices about HIV prevention by creating a helpful tool for family planning clinics, making it easier for them to access options like PrEP.
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Improving access to PrEP for women during contraceptive counseling
This study is looking to help women get better information about PrEP during their family planning visits by creating a helpful guide that makes it easier to understand their options, so they can make informed choices about their health.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.