Helping pregnant and breastfeeding women in Zambia make informed decisions about HIV prevention

Promoting PrEP shared decision-making and adherence among pregnant and breastfeeding women in Zambia

NIH-funded research Univ of North Carolina Chapel Hill · NIH-10742941

This study is all about helping pregnant and breastfeeding women in Zambia make informed choices about using a medication called PrEP to prevent HIV, by encouraging open conversations that take their personal feelings and needs into account.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill NIH-funded
Lab location1 site (Chapel Hill, United States)
Project IDNIH-10742941 on NIH RePORTER

What this research studies

This research focuses on improving the decision-making process for pregnant and breastfeeding women in Zambia regarding the use of pre-exposure prophylaxis (PrEP) to prevent HIV. It aims to develop and evaluate behavioral interventions that promote person-centered discussions about PrEP, ensuring that women's values and preferences are considered. The study will involve identifying key factors that influence women's decisions about PrEP through a mixed methods approach, which includes both qualitative and quantitative data collection. By enhancing shared decision-making, the research seeks to improve adherence to PrEP among this vulnerable population.

Who could benefit from this research

Good fit: Ideal candidates for this research are pregnant and breastfeeding women in Zambia who are at risk of HIV.

Not a fit: Patients who are not pregnant or breastfeeding, or those who are not at risk of HIV, may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better-informed decisions and increased adherence to HIV prevention methods among pregnant and breastfeeding women.

How similar studies have performed: Previous research has shown that person-centered approaches in healthcare can significantly improve patient adherence and outcomes, suggesting potential success for this approach.

Where this research is happening

Chapel Hill, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.