NIH-funded research R01 grant

Using automated speech analysis to diagnose frontotemporal dementia

Official title: Automated speech assessment for diagnosis of FTD spectrum disorders

Funded at Mayo Clinic Rochester · NIH-11082470 · Data updated 2026-11-12

This study is looking at how a new online speech test can help doctors better diagnose frontotemporal dementia and similar conditions by spotting unique speech patterns, making it easier and faster for patients to get the help they need.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMayo Clinic Rochester
NIH-funded
Lab location1 site (Rochester, United States)
Project startMay 1, 2024
Project endJanuary 31, 2029
Funding year2025
Award (this year)$723,711
NIH project number5R01AG083832-02
Project IDNIH-11082470 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include adults under 60 years old who are experiencing speech changes or symptoms related to dementia.

Less likely to help

Patients with dementia types unrelated to frontotemporal degeneration may not benefit from this research.

What this research studies

This research investigates how automated speech assessments can improve the diagnosis of frontotemporal dementia (FTD) and related disorders. By utilizing a web-based speech exam, the study aims to identify specific speech characteristics that may indicate the presence of FTD. The approach leverages deep learning techniques to analyze speech patterns, potentially allowing for more accurate and timely diagnoses. This innovative method seeks to overcome limitations of previous studies by using a broader dataset that includes various disorders with similar speech changes.

Why it matters

Potential benefit: If successful, this research could lead to earlier and more accurate diagnoses of frontotemporal dementia, improving patient outcomes and treatment options.

How similar studies have gone: Previous research has shown promise in using speech analysis for diagnosing dementia, but this approach aims to address limitations in those studies, making it a novel endeavor.

Where this research is happening

  • Mayo Clinic Rochester
    Rochester, United States
    Active

Researchers

  • Principal investigator: Botha, Hugo — Mayo Clinic Rochester
  • Study coordinator: Botha, Hugo

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.