NIH-funded research R01 grant

Caregiver Speech and Infant Brain Development in Siblings of Children with Autism

Official title: Caregiver Speech and Brain-Behavior Development in Infants At-Risk for ASD

Funded at University of Minnesota · NIH-11540457 · Data updated 2026-11-12

This project follows babies who have an older sibling with autism to explore how caregiver talk and everyday interactions relate to early brain and behavior development.

More Speech research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Minnesota
NIH-funded
Lab location1 site (Minneapolis, United States)
Project startMay 20, 2022
Project endApril 30, 2027
Funding year2026
Award (this year)$32,400
NIH project number3R01DC019660-05S1
Project IDNIH-11540457 on NIH RePORTER

Who could benefit from this research

Could help

Infants at high familial risk for autism (e.g., having an older sibling with autism) and whose families consent to home language recording and lab-based assessments.

Less likely to help

Infants without elevated familial risk or those whose families choose not to participate may not benefit from this specific study.

What this research studies

If your baby has a higher family risk for autism, this study will collect home language recordings at 6 and 12 months to see how caregiver speech and infant vocalizations relate to brain and behavior growth. Researchers will use advanced computer tools to measure how much and what kind of talk happens in daily life, plus laboratory play sessions to capture detailed interactions. The goal is to identify early patterns that could inform gentle, presymptomatic steps to support development. The study collaborates with the IBIS Network to track 250 high-risk infants over time. Participation could help us learn how to support children at risk for autism earlier and more effectively.

Why it matters

Potential benefit: If successful, findings could guide earlier, more personalized strategies to support communication and brain development in infants at risk for autism.

How similar studies have gone: Prior research in similar cohorts has shown meaningful links between early caregiver interactions and later developmental trajectories, supporting the approach of this study.

Where this research is happening

  • University of Minnesota
    Minneapolis, United States
    Active

Researchers

  • Principal investigator: Swanson, Meghan Rae — University of Minnesota
  • Study coordinator: Swanson, Meghan Rae

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.