NIH-funded research R01 grant

Overlap between how we speak and how we hold words in memory

Official title: The overlap of speech production and verbal working memory

Funded at Duke University · NIH-11598542 · Data updated 2026-11-12

A Duke-led project studies how the brain that talks relates to keeping verbal information in working memory, using advanced brain recordings from patients already undergoing medical care.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionDuke University
NIH-funded
Lab location1 site (Durham, United States)
Project startSeptember 20, 2023
Project endMay 31, 2028
Funding year2026
Award (this year)$39,445
NIH project number3R01NS129703-04S1
Project IDNIH-11598542 on NIH RePORTER

Who could benefit from this research

Could help

Patients with neurosurgical conditions who are already undergoing clinical monitoring and consent to participate in brain-recording studies may be eligible.

Less likely to help

Patients not undergoing neurosurgical monitoring or who do not consent to brain-recording research would not participate or benefit.

What this research studies

This project builds on a prior study to examine the shared brain systems for speech production and verbal working memory. It uses direct intracranial recordings with high-density micro-electrocorticography to observe brain activity in neurosurgical patients. The administrative supplement focuses on organizing and standardizing the growing data, expanding storage and computing capacity, and applying new data-sharing standards to make results reusable. No new scientific aims are added; the work remains within the approved plan of the parent award. The effort addresses increased costs and data-management needs arising from larger, richer datasets.

Why it matters

Potential benefit: If successful, it could improve understanding of speech and memory processes, potentially informing therapies for speech disorders and cognitive communication deficits.

How similar studies have gone: Previous work has shown meaningful insights from direct brain recordings about speech and memory, with ongoing advances in data-sharing standards.

Where this research is happening

  • Duke University
    Durham, United States
    Active

Researchers

  • Principal investigator: Cogan, Gregory B — Duke University
  • Study coordinator: Cogan, Gregory B

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.