Using advanced methods to analyze patient data while protecting privacy
Official title: Decentralized differentially-private methods for dynamic data release and analysis
Funded at Yale University · NIH-11003369 · Data updated 2026-11-12
This study is working on new ways for hospitals to use patient data to better understand and treat chronic diseases while keeping your personal information safe and private.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | January 1, 2023 |
| Project end | December 31, 2025 |
| Funding year | 2025 |
| Award (this year) | $540,615 |
| NIH project number | 5R01LM013712-08 |
| Project ID | NIH-11003369 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with chronic diseases who are receiving care at participating healthcare institutions.
✕Less likely to help
Patients with acute conditions or those not receiving care at the participating institutions may not benefit from this research.
What this research studies
This research focuses on developing innovative algorithms that allow healthcare institutions to analyze large datasets without compromising patient privacy. By keeping data at each healthcare center and using decentralized methods, the project aims to enhance the accuracy of predictive analytics tools for chronic diseases. Patients' data will be utilized to improve understanding and treatment of conditions while ensuring their information remains secure and confidential. The approach addresses concerns about data sharing and consent, making it easier for institutions to contribute valuable insights.
Why it matters
Potential benefit: If successful, this research could lead to improved predictive tools that enhance patient care and outcomes for chronic diseases.
How similar studies have gone: Previous research has shown promise in using decentralized methods for data analysis, indicating potential for success in this approach.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Ohno-Machado, Lucila — Yale University
- Study coordinator: Ohno-Machado, Lucila
Related research
Other NIH-funded projects on the same topics.
-
Aging Well with HIV: Alcohol, Risk Reduction, and Education Center (AWAR3E)
A center at Yale is exploring how aging with HIV interacts with alcohol use to create inflammation and frailty, with the goal of finding biomarkers and potential treatments.
-
Community Health Worker–Led Hypertension Prevention and Control in Nepal
A community health worker–driven approach in Nepal aims to prevent and control high blood pressure among adults by bringing education and care directly to communities and homes.
-
Community health worker-led hypertension prevention and control in Nepal
A community health worker–led program in Nepal aims to help adults prevent and better control high blood pressure through home visits, education, and ongoing support.
-
Adapting a mobile health tool to boost HIV outcomes for older adults with HIV in Ukraine
A mobile health platform called PositiveLinks would be adapted for older adults with HIV in Ukraine to help them stay engaged in care and improve treatment success.
-
Behavioral and neural links between spoken language sounds and written words in young children
This grant studies how young children learn from listening and reading to improve literacy, by looking at how sound patterns transfer to written language.
-
Understanding how autoimmunity causes myasthenia gravis
This project looks at why the immune system attacks the nerve-muscle connection in myasthenia gravis and how different patient groups are affected.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.