NIH-funded research R01 grant

Understanding how the brain turns speech into meaning

Official title: Characterizing the generative mechanisms underlying the cortical tracking of natural speech

Funded at University of Rochester · NIH-11354007 · Data updated 2026-11-12

A big neuroscience question is being studied to explain how adults process natural speech in real life, with findings that could help people who struggle to understand spoken language.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Rochester
NIH-funded
Lab location1 site (Rochester, United States)
Project startJuly 7, 2023
Project endJune 30, 2028
Funding year2026
Award (this year)$385,000
NIH project number5R01DC021140-04
Project IDNIH-11354007 on NIH RePORTER

Who could benefit from this research

Could help

Adults with typical or atypical speech processing who are curious about how their brains process natural speech.

Less likely to help

People without any interest in brain mechanisms of speech or those outside the adult range may not benefit directly.

What this research studies

This grant investigates how the human brain follows natural speech by looking at brain activity and speech patterns to see whether rhythmic brain timing or sequence of brief brain responses drives how we understand spoken language. Researchers will use naturalistic listening tasks and brain recording methods to compare theories about how the brain encodes speech at multiple timescales. The study focuses on adults and aims to clarify the neural mechanisms behind speech comprehension in everyday communication. The results could inform better approaches to treatments or interventions for individuals with speech and language difficulties.

Why it matters

Potential benefit: If successful, the work could lead to improved strategies for diagnosing and treating speech comprehension problems and inform the design of better hearing and communication aids.

How similar studies have gone: Previous research has explored brain tracking of speech, but there is ongoing debate about the exact mechanisms and this study aims to provide clearer evidence.

Where this research is happening

  • University of Rochester
    Rochester, United States
    Active

Researchers

  • Principal investigator: Lalor, Edmund — University of Rochester
  • Study coordinator: Lalor, Edmund

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.