Understanding how the brain controls precise reaching movements
Official title: Spatiotemporal encoding of goal-directed reaching across early cerebellar circuitry
Funded at University of Colorado Denver · NIH-11142303 · Data updated 2026-11-12
This study is looking at how a part of the brain called the cerebellum helps mice make precise movements when reaching for things, which could help us understand better ways to treat movement disorders in people.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project start | January 1, 2024 |
| Project end | December 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $74,284 |
| NIH project number | 5F32NS134561-02 |
| Project ID | NIH-11142303 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research would be individuals with movement disorders, particularly those experiencing issues with reaching and coordination.
✕Less likely to help
Patients with non-motor related conditions or those not experiencing any movement disorders may not receive direct benefits from this research.
What this research studies
This research investigates the role of the cerebellum in coordinating precise movements, particularly focusing on how the brain generates the necessary signals for goal-directed reaching. Using advanced two-photon calcium imaging techniques, the study will observe the activity of specific neurons in the cerebellar cortex of mice as they perform reaching tasks. By analyzing how information about target locations and movement goals is processed, the research aims to uncover the underlying mechanisms that contribute to movement precision. This could lead to a better understanding of motor control and potential interventions for movement disorders.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of motor control, potentially leading to improved treatments for conditions that affect movement precision.
How similar studies have gone: Previous research has shown promising results in understanding cerebellar function and its role in motor control, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Colorado Denver
Aurora, United States Active
Researchers
- Principal investigator: Nguyen, Katrina — University of Colorado Denver
- Study coordinator: Nguyen, Katrina
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.