Human Trisome Project in Latin America Network
Official title: Human Trisome Project - Latin America Network
Funded at University of Colorado Denver · NIH-11594209 · Data updated 2026-11-12
A large, multi-site study of people with Down syndrome across Latin America to better understand health and aging in DS.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project start | September 20, 2024 |
| Project end | May 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $269,101 |
| NIH project number | 3U01HD116469-02S5 |
| Project ID | NIH-11594209 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals with Down syndrome across participating sites, including diverse ages and clinical backgrounds, who enroll according to the protocol.
✕Less likely to help
Some participants may not experience direct benefits during the study period, as findings accumulate over time.
What this research studies
This project connects six research sites, including five in Latin America, to study people with Down syndrome as part of the NIH INCLUDE CDP program. It builds on the common protocol for collecting data and biospecimens, with IRB approvals and data sharing across sites. Participants may contribute health information, biological samples, and long-term follow-up to help uncover how trisomy 21 affects aging, health, and development. The effort emphasizes collaboration, training, and streamlined regulatory processes to enable meaningful discoveries.
Why it matters
Potential benefit: Better understanding of health risks and aging in Down syndrome, which could inform future care and interventions.
How similar studies have gone: Previous similar cohorts have accelerated understanding of Down syndrome health trajectories through shared protocols and data sharing.
Where this research is happening
-
University of Colorado Denver
Aurora, United States Active
Researchers
- Principal investigator: Espinosa, Joaquin M. — University of Colorado Denver
- Study coordinator: Espinosa, Joaquin M.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.